Results 101 to 110 of about 447,541 (315)
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi +14 more
wiley +1 more source
LINEAR POSITIONING ERRORS OF 3 - AXIS MACHINE TOOL [PDF]
This paper presents results of 3-axis CNC machine tool diagnostics performed with XL-80 laser interferometer and XC-80 environmental compensation unit, including pressure, humidity and temperature sensors.
Jerzy JÓZWIK +3 more
doaj
MITF maintains genome stability in nonmelanocyte lineages
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
High-accuracy three-dimensional miniature components and microstructures are increasingly in demand in the sector of electro-optics, automotive, biotechnology, aerospace and information-technology industries.
Wardle, F, Cheng, K, Huo, D
core +1 more source
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski +12 more
wiley +1 more source
Beam search heuristics for the single machine scheduling problem with linear earliness and quadratic tardiness costs [PDF]
In this paper, we consider the single machine scheduling problem with linear earliness and quadratic tardiness costs, and no machine idle time. We present heuristic algorithms based on the beam search technique.
Jorge M. S. Valente
core
Linear generators for direct drive marine renewable energy converters [PDF]
This thesis is concerned with the development of linear generators for use as the power take off mechanism in marine renewable energy converters. Delivering significant power at the low velocities demanded by wave and tidal stream energy converters ...
Baker, Nicholas Jon
core
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
Five-Axis Machine Tool Condition Monitoring Using dSPACE Real-Time System
This paper presents the design, development and SIMULINK implementation of the lumped parameter model of C-axis drive from GEISS five-axis CNC machine tool.
Longstaff, Andrew P. +7 more
core +1 more source
Weighted Linear Loss Projection Twin Support Vector Machine for Pattern Classification
Based on the recently proposed projection twin support vector machine (PTSVM) and least squares projection twin support vector machine (LSPTSVM), in this paper, we propose a weighted linear loss projection twin support vector machine, namely WLPTSVM for ...
Sugen Chen, Junfeng Cao, Zhong Huang
doaj +1 more source

