Results 51 to 60 of about 1,982,495 (283)
Mapping the evolution of mitochondrial complex I through structural variation
FEBS Letters, EarlyView.Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin +2 more
wiley +1 more source
Multivariate Generalized Linear Mixed Models for Count Data
Austrian Journal of StatisticsUnivariate regression models have rich literature for counting data. However, this is not the case for multivariate count data. Therefore, we present the Multivariate Generalized Linear Mixed Models framework that deals with a multivariate set of ...
Guilherme Parreira da Silva +4 more
doaj +1 more source
Spatial Autoregressive Modeling on Linear Mixed Models for Dependency Between Regions
Aceh International Journal of Science and Technology, 2023 This study develops a linear mixed model (LMM) that includes spatial effects between regions with a spatial autoregressive model (SAR model). Between observations (regions) on that LMM are usually assumed to be independent. However, these assumptions are
Timbang Sirait
doaj +1 more source
Linear quantile mixed models [PDF]
, 2011 Dependent data arise in many studies. For example, children with the same parents or living in neighbouring geographic areas tend to be more alike in many characteristics than individuals chosen at random from the population at large; observations taken ...
Bottai, M, Geraci, M
core
Two-period linear mixed effects models to analyze clinical trials with run-in data when the primary outcome is continuous: Applications to Alzheimer\u27s disease. [PDF]
, 2019 Introduction: Study outcomes can be measured repeatedly based on the clinical trial protocol before randomization during what is known as the run-in period.
Aschenbrenner, Andrew J +9 more
core +2 more sources
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
D-optimal designs formulti-response linear mixed models [PDF]
, 2018 Linear mixed models have become popular in many statistical applications duringrecent years. However design issues for multi-response linear mixed models are rarelydiscussed.
Liu, Xin, Wong, Weng Kee, Yue, Rong-Xian
core
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
On non-negative estimation of variance components in mixed linear models
Journal of Advanced Research, 2016 Alternative estimators have been derived for estimating the variance components according to Iterative Almost Unbiased Estimation (IAUE). As a result two modified IAUEs are introduced.
Heba A. El Leithy +2 more
doaj +1 more source
FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source