Results 61 to 70 of about 658,808 (305)

Quasi-Monte Carlo EM algorithm for MLEs in generalized linear mixed models

open access: yes, 1998
Inferences for generalized linear mixed models are greatly hampered by the intractable integrated likelihood. In this paper numerical integration based on Quasi-Monte Carlo method is used to approximate the integral of the EM algorithm and then to fit ...
Robin Thompson   +3 more
core   +1 more source

Modeling Multiple Item Context Effects With Generalized Linear Mixed Models

open access: yesFrontiers in Psychology, 2019
Item context effects refer to the impact of features of a test on an examinee's item responses. These effects cannot be explained by the abilities measured by the test. Investigations typically focus on only a single type of item context effects, such as
Norman Rose   +6 more
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Bayesian Boosting for Linear Mixed Models

open access: yesCoRR, 2021
Boosting methods are widely used in statistical learning to deal with high-dimensional data due to their variable selection feature. However, those methods lack straightforward ways to construct estimators for the precision of the parameters such as variance or confidence interval, which can be achieved by conventional statistical methods like Bayesian
Boyao Zhang   +4 more
openaire   +2 more sources

Prediction in linear mixed models

open access: yes, 2004
Following estimation of effects from a linear mixed model, it is often useful to form predicted values for certain factor/variate combinations. The process has been well defined for linear models, but the introduction of random effects into the model ...
Gogel, Beverley   +9 more
core   +1 more source

Spatial Autoregressive Modeling on Linear Mixed Models for Dependency Between Regions

open access: yesAceh International Journal of Science and Technology, 2023
This study develops a linear mixed model (LMM) that includes spatial effects between regions with a spatial autoregressive model (SAR model). Between observations (regions) on that LMM are usually assumed to be independent. However, these assumptions are
Timbang Sirait
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Prediction of genetic value in F3 populations of Avena sativa L. using Reml/Blup

open access: yesCrop Breeding and Applied Biotechnology, 2005
In genetics and breeding studies it is common to conduct experiments of fixed (sowing method) and random (populations) factors. Therefore, the most appropriate statistic analyses would use mixed linear models.
Jefferson Luís Meirelles Coimbra   +6 more
doaj  

On non-negative estimation of variance components in mixed linear models

open access: yesJournal of Advanced Research, 2016
Alternative estimators have been derived for estimating the variance components according to Iterative Almost Unbiased Estimation (IAUE). As a result two modified IAUEs are introduced.
Heba A. El Leithy   +2 more
doaj   +1 more source

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