Results 91 to 100 of about 2,011,711 (312)
Purpose Humeral shaft fractures account for 1.2% of all fractures in adults. Regardless of the treatment approach, the consequences of immobility can lead to decreased functional capacity in these individuals.
Pedro A.C. Silva +7 more
doaj +1 more source
Model-based Prediction of Length of Stay for Rehabilitating Stroke Patients
Accurate length-of-stay (LOS) estimates have an impact on medical costs for stroke patients. Most studies have reported only descriptive sample means or have provided linear-model-based estimates for LOS.
Chien-Lin Lin +6 more
doaj +1 more source
AbstractGeneralized Linear Modeling (GLM) unifies several statistical techniques, providing a stable and modular foundation on which to build a useful working knowledge of statistical modeling. GLMs enable a re-interpretation of previously learned ANOVA and regression techniques and integrate well with more advanced modeling techniques introduced in ...
openaire +5 more sources
Tau acetylation at K331 has limited impact on tau pathology in vivo
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Using n-alkanes to estimate diet composition of herbivores: a novel mathematical approach
N-alkanes are long-chain saturated hydrocarbons occurring in plant cuticles that can be used as chemical markers for estimating the diet composition of herbivores.
P. Barcia +3 more
doaj +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Araştırmalarda uygun istatistiksel tekniğin belirlenmesi, araştırmanın metodolojik tasarımının yanı sıra analizin amacı, örneklem büyüklüğü ve yapısı, verilerin ve veri setinin karakteristiğinin de dikkate alınmasını gerektiren zorlayıcı bir aşamadır ...
İrem Çelik, Sibel Urlu, Ergul Demir
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Bayesian outliers functions for linear models. [PDF]
This paper introduces two new diagnostic tools: the Bayesian outlier curve (BOC) and the Sequential Bayesian outlier curve (SEBOC). Both are built using the posterior odds for every possible number of outliers in a scale contaminated linear model.
Tíao, George C., Peña, Daniel
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