Results 81 to 90 of about 2,011,711 (312)

Inbreeding depression in Holstein cattle in Brazil

open access: yesRevista Brasileira de Zootecnia
The objective of this study was to evaluate inbreeding depression in Holstein cows in Brazil, considering their 305-day milk production (MP), age of first calving (AFC), and calving interval (CI).
Mário Henrique Magalhães Araújo da Silva   +5 more
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Diagnostics for generalised linear mixed models [PDF]

open access: yes
Generalized linear mixed models are generalized linear models that include random effects varying between clusters or 'higher-level' units of hierarchically structured data. Such models can be estimated using gllamm.
Sophia Rabe-Hesketh, Anders Skrondal
core  

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Boosting Correlation Based Penalization in Generalized Linear Models [PDF]

open access: yes, 2007
In high dimensional regression problems penalization techniques are a useful tool for estimation and variable selection. We propose a novel penalization technique that aims at the grouping effect which encourages strongly correlated predictors to be in ...
Tutz, Gerhard, Ulbricht, Jan
core   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Forecasting interest rate swap spreads using domestic and international risk factors: Evidence from linear and non-linear models. [PDF]

open access: yes
This paper explores the ability of factor models to predict the dynamics of US and UK interest rate swap spreads within a linear and a non-linear framework.
Costas Milas   +2 more
core  

The Linear Voting Model.

open access: yes, 2016
We study voting models on graphs. In the beginning, the vertices of a given graph have some initial opinion. Over time, the opinions on the vertices change by interactions between graph neighbours. Under suitable conditions the system evolves to a state in which all vertices have the same opinion. In this work, we consider a new model of voting, called
Colin Cooper, Nicolas Rivera
openaire   +3 more sources

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

A survey on generalized linear models (GLMS) and their diagnostic tools

open access: yes, 2017
An important statistical development in the last four decades has been the advancement in the field of regression analysis for a variety of response variables under the umbrella of an exponential family of distributions.
Alsidrani, Fahad Abdulaziz
core  

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