Results 91 to 100 of about 12,380,363 (249)

Full subsets linear mixed effects regression model statistics for subyearling Chinook productivity rate models.

open access: yes, 2018
Full subsets linear mixed effects regression model statistics for subyearling Chinook productivity rate models.
Timothy J. Beechie (731529)   +6 more
core   +1 more source

A generalised likelihood framework for partially observed capture-recapture-recovery models [PDF]

open access: yes, 2013
We provide a closed form likelihood expression for multi-state mark-recapture-recovery data when the state of an individual may be only partially observed.
McCrea, Rachel S.   +2 more
core   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Exact Hypothesis Tests for Log-linear Models with exactLoglinTest [PDF]

open access: yes
This manuscript overviews exact testing of goodness of fit for log-linear models using the R package exactLoglinTest. This package evaluates model fit for Poisson log-linear models by conditioning on minimal sufficient statistics to remove nuisance ...
Brian Caffo
core  

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Error bounds for the convex loss Lasso in linear models

open access: yes, 2017
In this paper we investigate error bounds for convex loss functions for the Lasso in linear models, by first establishing a gap in the theory with respect to the existing error bounds.
Deléamont, Pierre-Yves   +3 more
core   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

Simulation-based prior knowledge elicitation for parametric Bayesian models

open access: yesScientific Reports
A central characteristic of Bayesian statistics is the ability to consistently incorporate prior knowledge into various modeling processes. In this paper, we focus on translating domain expert knowledge into corresponding prior distributions over model ...
Florence Bockting   +2 more
doaj   +1 more source

Comparing non-linear mathematical models to describe growth of different animals

open access: yesActa Scientiarum: Animal Sciences, 2017
The main objective of this study was to compare the goodness of fit of five non-linear growth models, i.e. Brody, Gompertz, Logistic, Richards and von Bertalanffy in different animals. It also aimed to evaluate the influence of the shape parameter on the
Jhony Tiago Teleken   +2 more
doaj   +1 more source

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