Results 91 to 100 of about 590,268 (302)

Comparing non-linear mathematical models to describe growth of different animals

open access: yesActa Scientiarum: Animal Sciences, 2017
The main objective of this study was to compare the goodness of fit of five non-linear growth models, i.e. Brody, Gompertz, Logistic, Richards and von Bertalanffy in different animals. It also aimed to evaluate the influence of the shape parameter on the
Jhony Tiago Teleken   +2 more
doaj   +1 more source

Distribution free goodness-of-fit tests for linear processes [PDF]

open access: yes, 2004
This article proposes a class of goodness-of-fit tests for the autocorrelation function of a time series process, including those exhibiting long-range dependence.
Velasco Gómez, Carlos   +8 more
core   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

Statistics: For Engineers and Scientists [PDF]

open access: yes, 2011
Statistics for Engineers and Scientists stands out for its crystal clear presentation of applied statistics. Suitable for a one or two semester course, the book takes a practical approach to methods of statistical modeling and data analysis that are most
Navidi, William
core  

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

The limiting power of autocorrelation tests in regression models with linear restrictions [PDF]

open access: yes
It is well known that the Durbin-Watson and several other tests for first-order autocorrelation have limiting power of either zero or one in a linear regression model without an intercept, and tend to a constant lying strictly between these values when ...
Wan, Alan, Zou, Guohua, Banerjee, Anurag
core  

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Simulation-based prior knowledge elicitation for parametric Bayesian models

open access: yesScientific Reports
A central characteristic of Bayesian statistics is the ability to consistently incorporate prior knowledge into various modeling processes. In this paper, we focus on translating domain expert knowledge into corresponding prior distributions over model ...
Florence Bockting   +2 more
doaj   +1 more source

Bayes Linear Variance Learning for Mixed Linear Temporal Models [PDF]

open access: yes, 2012
Modelling of complex corroding industrial systems is ritical to effective inspection and maintenance for ssurance of system integrity. Wall thickness and corrosion rate are modelled for multiple dependent corroding omponents, given observations of ...
RANDELL, DAVID
core  

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

open access: yesMolecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute   +4 more
wiley   +1 more source

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