Results 31 to 40 of about 538,044 (257)

Clinical Course and Impact of Breaks in Therapy for Children With Relapsed/Refractory Solid Tumors

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction Pediatric relapsed or refractory (R/R) solid tumors carry a dismal prognosis, and postrelapse patient experiences are not well described. We present postrelapse outcomes, including number of R/R events and subsequent therapy regimens.
Matthew T. McEvoy   +5 more
wiley   +1 more source

UNA GENERALIZACIÓN DE LA ESTADÍSTICA DE COOK UNA GENERALIZACIÓN DE LA ESTADÍSTICA DE COOK

open access: yesRevista Colombiana de Estadística, 2001
This paper presents a generalization of the Cook's statistics useful in the identification of influential observations in the least squares estimation of the multiple regression parameters.En este artículo se presenta una generalización de la estadística
Jiménez M. José
doaj  

Criterion‐Related Validity of the Neuropsychological Quick Assessment for Screening Cognitive, Motor, and Behavioral Impairments in Patients With Pediatric Brain Tumors: An Observational Pilot Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Neuropsychological complications may impair the qualitative prognosis of patients with pediatric brain tumors. However, multifaceted evaluations cannot be conducted in all patients because they are time consuming and burdensome for patients.
Ami Tabata   +9 more
wiley   +1 more source

Exact Hypothesis Tests for Log-linear Models with exactLoglinTest

open access: yesJournal of Statistical Software, 2006
This manuscript overviews exact testing of goodness of fit for log-linear models using the R package exactLoglinTest. This package evaluates model fit for Poisson log-linear models by conditioning on minimal sufficient statistics to remove nuisance ...
Brian Caffo
doaj   +3 more sources

A High Dimensional Omnibus Regression Test

open access: yesStats
Consider regression models where the response variable Y only depends on the p×1 vector of predictors x=(x1,…,xp)T through the sufficient predictor SP=α+xTβ. Let the covariance vector Cov(x,Y)=ΣxY.
Ahlam M. Abid   +2 more
doaj   +1 more source

The Efficacy and Safety of Bevacizumab/Irinotecan/Temozolomide (BIT) for Relapsed/Refractory Neuroblastoma: The UK Children's Cancer and Leukaemia Group Experience

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Patients with high‐risk neuroblastoma who either are refractory to induction chemotherapy or relapse following multi‐modal treatment have a dismal prognosis. Based on data from the BEACON trial, since 2021 the UK national guidelines recommend bevacizumab, irinotecan, and temozolomide (BIT) for patients with relapsed/refractory ...
Thomas J. Jackson   +20 more
wiley   +1 more source

Basics of Statistics for Clinical Research in Hand Surgery

open access: yesRevista Iberoamericana de Cirugía de la Mano, 2018
Statistics, the science of numerical evaluation, helps in determining the real value of a hand surgical intervention. Clinical research in hand surgery cannot improve without considering the application of the most appropriate statistical procedures. The
Roberto S. Rosales, Isam Atroshi
doaj   +1 more source

Do you know your r2?

open access: yesADMET and DMPK, 2020
The prediction of solubility of drugs usually calls on the use of several open-source/commercially-available computer programs in the various calculation steps.
Alex Avdeef
doaj   +1 more source

Implementing Health‐Related Quality of Life Assessment in Pediatric Oncology: A Feasibility Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background There is growing interest in embedding health‐related quality of life (HRQoL) assessment and patient‐reported outcome measures (PROMs) within clinical cancer care. This study evaluated the feasibility, acceptability, and usability of implementing an electronic PROM (ePROM) platform to measure HRQoL in children with cancer ...
Mikaela Doig   +13 more
wiley   +1 more source

Treatment Decision‐Making Roles and Preferences Among Adolescents and Young Adults With Cancer

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Decision‐making (DM) dynamics between adolescents and young adults (AYAs) with cancer, parents, and oncologists remain underexplored in diverse populations. We examined cancer treatment DM preferences among an ethnically and socioeconomically diverse group of AYAs and their parents.
Amanda M. Gutierrez   +14 more
wiley   +1 more source

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