Results 51 to 60 of about 590,268 (302)

Testing structural change in partially linear single-index models with error-prone linear covariates [PDF]

open access: yes, 2012
Motivated by an analysis of a real data set from Duchenne Muscular Dystrophy (Andrews and Herzberg, 1985), we propose a new test of structural change for a class of partially linear single-index models with error-prone linear covariates.
Huang, Zhensheng, Pang, Zhen, Hu, Tao
core   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

UN CRITERIO PARA IDENTIFICAR DATOS ATÍPICOS UN CRITERIO PARA IDENTIFICAR DATOS ATÍPICOS

open access: yesRevista Colombiana de Estadística, 2004
This paper present a method to determine the observations that are outliers in a model of multiple linear regression; these data will be established according to the change that is presented on the sum of the squares of residual of the model.En este ...
Jiménez Moscoso José Alfredo
doaj  

Regularization Methods Based on the Lq-Likelihood for Linear Models with Heavy-Tailed Errors

open access: yesEntropy, 2020
We propose regularization methods for linear models based on the Lq-likelihood, which is a generalization of the log-likelihood using a power function. Regularization methods are popular for the estimation in the normal linear model.
Yoshihiro Hirose
doaj   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

Modified Chi-Squared Goodness-of-Fit Tests for Continuous Right-Skewed Response Generalized Linear Models

open access: yesMathematics
Generalized linear models are applied for data analysis in various areas. One of the most important steps in fitting the model is to check the goodness-of-fit; however, there is a lack of such tests.
Vilijandas Bagdonavičius   +1 more
doaj   +1 more source

Sparse nested Markov models with log-linear parameters [PDF]

open access: yes, 2013
Hidden variables are ubiquitous in practical data analysis, and therefore modeling marginal densities and doing inference with the resulting models is an important problem in statistics, machine learning, and causal inference.
Robins, James   +7 more
core  

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

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