Results 81 to 90 of about 64,667 (273)

Deciphering the Role of Cancer Stem Cells in Breast Cancer Brain Colonization Using a Novel Patient‐Derived Model

Advanced Healthcare Materials, EarlyView.
This study shows that stem‐like cells isolated from breast cancer brain metastases drive the spread and growth of tumors in the brain. Among them, a highly adhesive subgroup initiates metastasis and resists many drugs. By closely reflecting patient tumors, these models help identify new targets and improve the development of effective treatments ...
Stefania Faletti, Cristina Richichi, Daniela Osti, Elena Ceccacci, Giovanni Bertalot, Camilla Cerutti, Giuseppina Giardina, Adriana Marinaro, Brunella Costanza, Valentina Gambino, Elena Zaccheroni, Daniela Tosoni, Maria G. Filippone, Marcello Del Corvo, Yinxiu Zhan, Teresa Gravina, Davide Corà, Monica Patanè, Bianca Pollo, Maria Giovanna Jodice, Salvatore Pece, Babette B. Weksler, Ignacio A. Romero, Pierre‐Olivier Couraud, Elisabetta Munzone, Massimiliano Del Bene, Francesco DiMeco, Giuliana Pelicci   +27 more
wiley   +1 more source

A Parametric Six-Step Method for Second-Order IVPs with Oscillating Solutions

Mathematics
In this paper, we develop an explicit symmetric six-step method for the numerical solution of second-order initial value problems (IVPs) with oscillating solutions. The proposed method is phase-fitted and incorporates a free coefficient as a parameter to
Dimitris F. Papadopoulos
doaj   +1 more source

A Superhydrophobic 3D Cell Culture System Reveals the Mechanobiological Role of Cancer‐Associated Fibroblasts in Prostate Cancer Metastasis

Advanced Healthcare Materials, EarlyView.
A superhydrophobic 3D cell culture platform enables rapid and consistent formation of heterotypic tumor–stroma clusters, and reveals how physiological shear conditions influence metastatic signaling. Mechanical stimulation of cancer‐associated fibroblasts promotes sustained cytokine secretion and survival‐promoting pathways, showing how multicellular ...
Alexandria T. Carter, Abigail R. Fabiano, Ehsan Aalaei, Jason Deng, Dakota E. Rostant, Michael R. King   +5 more
wiley   +1 more source

Numerical Simulation for Chaotic Financial Models

Journal of Applied Mathematics
The study introduces a novel numerical framework for chaotic financial models, characterized by sensitive dynamics. Our method diverges from traditional liberalization and subdivision approaches, directly tackling chaotic systems without simplification ...
Eneodo Janet Onoja, Gemeda Tolessa Lubo
doaj   +1 more source

Recapitulating Endochondral Ossification for Bone Repair: From Development to Engineering Strategy

Advanced Healthcare Materials, EarlyView.
This review summarizes the developmental basis of endochondral ossification (ECO) and its applications in bone tissue engineering (BTE). It first outlines the key biological processes and signaling pathways underlying ECO, then discusses biomaterial‐based engineering strategies derived from these principles, and finally highlights future directions for
Yiqi Su, Zihao He, Qianqian Chen, Long Chen, Caiyi Wei, Zijin Zhou, Jianhao Lin, Hui Li, Dan Xing   +8 more
wiley   +1 more source

High order second derivative multistep collocation methods for ordinary differential equations [PDF]

Iranian Journal of Numerical Analysis and Optimization
In this paper, we introduce second derivative multistep collocation meth-ods for the numerical integration of ordinary differential equations (ODEs).
S. Fazeli
doaj   +1 more source

Spin‐Split Edge States in Metal‐Supported Graphene Nanoislands Obtained by CVD

Advanced Materials, EarlyView.
Combining STM measurements and ab‐initio calculations, we show that zig‐zag edges in graphene nanoislands grown on Ni(111) by CVD retrieve their spin‐polarized edge states after intercalation of a few monolayers of Au. ABSTRACT Spin‐split states localized on zigzag edges have been predicted for different free‐standing graphene nanostructures.
Michele Gastaldo, Masoud Mansouri, Carlos Garcia‐Fernandez, Daniel Sánchez‐Portal, Aran Garcia‐Lekue, Gustavo Ceballos, Aitor Mugarza   +6 more
wiley   +1 more source

A Computational Study of the Boundary Value Methods and the Block Unification Methods for y″=f(x,y,y′)

Abstract and Applied Analysis, 2016
We derive a new class of linear multistep methods (LMMs) via the interpolation and collocation technique. We discuss the use of these methods as boundary value methods and block unification methods for the numerical approximation of the general second ...
T. A. Biala
doaj   +1 more source

Forecasting and Signal Extraction with Misspecified Models [PDF]

The paper illustrates and compares estimation methods alternative to maximum likelihood, among which multistep estimation and leave-one-out cross-validation, for the purposes of signal extraction, and in particular the separation of the trend from the ...
Tommaso Proietti
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