Results 111 to 120 of about 9,886,421 (293)
KAFA-Merge: Model Merging Method With Layer-Based Bayes+Linear Search
IEEE AccessIn this paper, we consider the model merging process for large language models (LLMs) under a two-stage optimization framework. Traditional merging methods usually apply fixed blending rates to all layers, which ignores the different levels of ...
Muzaffer Kaan Yuce +1 more
doaj +1 more source
A hyper-matheuristic approach for solving mixed integer linear optimization models in the context of data envelopment analysis. [PDF]
PeerJ Comput Sci, 2022 Gonzalez M +3 more
europepmc +1 more source
Molecular Oncology, EarlyView.AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou +5 more
wiley +1 more source
Optimal Policies for Conjunctive-Use and Cropping Pattern for Al-Wand Basin
مجلة النهرين للعلوم الهندسية, 2017 Applying conjunctive use between surface water and ground water is getting widely used at many regions in the world, due to the increasing need of water resources, especially when large quantities of water and for long time are used for irrigation ...
Amer Hassan Al-Haddad +1 more
doaj
DEA Problems under Geometrical or Probability Uncertainties of Sample Data [PDF]
This paper discusses the theoretical and practical aspects of new methods for solving DEA problems under real-life geometrical uncertainty and probability uncertainty of sample data.
Althaler, Karl S., Slavova, Tatjana
core
Optimizing Linear Optics Quantum Gates [PDF]
Physical Review Letters, 2005 5 pages, RevTeX, essentially identical with version in Phys. Rev.
openaire +4 more sources
Molecular Oncology, EarlyView.This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan +9 more
wiley +1 more source
Designing Nutritionally Adequate and Climate-Friendly Diets for Omnivorous, Pescatarian, Vegetarian and Vegan Adolescents in Sweden Using Linear Optimization. [PDF]
Nutrients, 2021 Eustachio Colombo P +3 more
europepmc +1 more source
Molecular Oncology, EarlyView.A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath +13 more
wiley +1 more source
Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids
Molecular Oncology, EarlyView.This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici +8 more
wiley +1 more source