Results 71 to 80 of about 5,277,522 (305)
A global optimization approach for the linear two-level program
Linear two-level programming deals with optimization problems in which the constraint region is implicity determined by another optimization problem. Mathematical programs of this type arise in connection with policy problems to which the Stackelberg ...
Tuy, Hoang, +2 more
core +1 more source
Organoids in pediatric cancer research
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
We prove that hashing $n$ balls into $n$ bins via a random matrix over $\mathbf{F}_2$ yields expected maximum load $O(\log n / \log \log n)$. This matches the expected maximum load of a fully random function and resolves an open question posed by Alon, Dietzfelbinger, Miltersen, Petrank, and Tardos (STOC '97, JACM '99). More generally, we show that the
Michael Jaber +2 more
openaire +3 more sources
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Chile has abundant solar and wind resources and renewable generation is becoming competitive with fossil fuel generation. However, due to renewable resource variability their large-scale integration into the electricity grid is not trivial.
Serguey A. Maximov +2 more
doaj +1 more source
Generalized Optimal Linear Orders
210 pages, M.S. Thesis of Rishi Bommasani (Cornell University, 2020; please cite: https://ecommons.cornell.edu/handle/1813/103195)
openaire +3 more sources
Reconstructing enzyme evolution by protein engineering
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Evaluation of the Acceptable Excise Rate on Palm-oil with Use of Linear Optimization Methods
The article is devoted to the actual matter of milk production quality and quantity regulation in circumstances of trade war between Russia and some other countries.
Andrey Arkadyevich Dmitriev
doaj
Investigating transcription factor dynamics in health and disease using FRAP
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source

