Results 131 to 140 of about 13,562,447 (238)
Molecular Oncology, EarlyView.This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault +12 more
wiley +1 more source
Joint state and parameter estimation for discrete-time polytopic linear parameter-varying systems
, 2017 Linear parameter-varying systems are very suitable for modelling nonlinear systems, since well-established methods from the linear-systems domain can be applied.
Donkers, M.C.F. +5 more
core +1 more source
Molecular Oncology, EarlyView.We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth +17 more
wiley +1 more source
Event-triggered control for discrete-time linear parameter-varying systems
, 2016 This paper examines a new event-triggered control design approach for discrete-time linear parameter-varying (LPV) system. To this purpose, a novel event-triggering framework is first introduced for LPV systems to reduce the data transmission of the ...
Meskin, N. +5 more
core +1 more source
FEBS Open Bio, EarlyView.Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley +1 more source
A parameter-varying fault detection filter design approach for polytopic uncertain linear systems
, 2014 This paper is concerned with the robust fault detection (FD) problem for a class of polytopic uncertain linear systems driven by a Wiener process. It is assumed that the state matrix is affinely depending on unknown but bounded time-varying parameters. A
Sun P(孙鹏) +2 more
core
FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
FEBS Open Bio, EarlyView.We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source
Linear Parameter-Varying Control of an F-16 Aircraft at High Angle of Attack
, 2005 To improve the aircraft capability at high angle of attack and expand the flight envelope, advanced linear parameter-varying (LPV) control methodologies are studied in this thesis with particular applications of actuator saturation control and switching ...
Lu, Bei
core
FEBS Open Bio, EarlyView.This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill +4 more
wiley +1 more source