Results 31 to 40 of about 663 (155)

A Case of Refractory Giant Porokeratosis, Treated With a New Treatment Approach Consisting of Ablative CO2 Laser and Methotrexate

Clinical Case Reports, Volume 14, Issue 6, June 2026.
ABSTRACT Combined fractional CO2 laser + MTX may be an option for refractory GPK, with vigilant biopsy confirmation and malignancy surveillance.
Ali Asilian, Mohammad Shoushtarizadeh, Sarah Seyedyousefi, Mohamad Beheshti, Malih Aminjavaheri   +4 more
wiley   +1 more source

Dermoscopy in pediatric dermatosis

Apollo Medicine, 2023
Introduction: Paediatric dermatoses differ from adult dermatoses with respect to clinical presentation, treatment and prognosis. These can be transitory, chronic and recurrent.
Gopalsing Rameshsing Rajput, Manas Chatterjee, Ruchi Hemdani   +2 more
doaj   +1 more source

Carrier screening in the reproductive setting—Are there medical implications for the heterozygote?—A guide for clinicians

Pregnancy, Volume 2, Issue 3, May 2026.
Abstract Carrier screening for genetic conditions performed preconception or during pregnancy allows identification of fetal risk for inherited autosomal recessive and X‐linked conditions. The goal is to identify at‐risk patients/couples and offer them reproductive options such as preimplantation genetic diagnosis, prenatal testing, or targeted newborn
Emily B. Rosenfeld, Nicole Kasatkin, Bi Liu Yu, Milen Velinov, Justin S. Brandt, Elena Ashkinadze   +5 more
wiley   +1 more source

A Multifaceted Holistic Review of the Literature on Scar Dermatoses

International Wound Journal, Volume 23, Issue 5, May 2026.
ABSTRACT Many cutaneous diseases originate or manifest in scars. Scars are areas of compromised skin, which renders them a vulnerable cutaneous district for diseases to develop. The pathophysiology explaining why some dermatoses grow in scars is not yet thoroughly explored. The present study reviews the present literature on scar dermatoses.
Dana Maria Khoury, Elias El Tayar, Edward Eid, Firas F. Haddad, Ossama Abbas, Mazen Kurban   +5 more
wiley   +1 more source

Successful Treatment of Refractory Disseminated Superficial Actinic Porokeratosis With Topical Ruxolitinib

Clinical Case Reports, Volume 14, Issue 4, April 2026.
ABSTRACT This is the first documented case of disseminated superficial actinic porokeratosis (DSAP) successfully treated with topical ruxolitinib. The patient experienced near‐complete clearance after three months, suggesting that topical JAK inhibition may be an effective and well‐tolerated option for refractory porokeratosis.
Joe Khodeir, Paul Ohanian, Marielena Ohanian   +2 more
wiley   +1 more source

Epidemiology and Genetics of Rheumatic Diseases Suggest a Constant Rate of DNA Damage as Underlying Cause

Immunology, Volume 177, Issue 4, Page 736-748, April 2026.
A constant rate of DNA damage that is not perfectly repaired will cause a constant rate of DNA mutations. The chance of mutation will increase if DNA is prone to damage, such as occurs in somatic hypermutation (SHM) hotspots and GC‐rich DNA. Thus, if one mutation‐prone DNA site drives disease, the age of onset of disease and degree of penetrance should
Piet C. de Groen
wiley   +1 more source

Linear Porokeratosis Along Blaschko’s Lines

Indian Journal of Dermatology, 2003
Linear porokeratosis of Mibelli (LPM), a variant of porokeratosis, usually appears in childhood, but may occur in middle life. Unilateral lesions frequently occur and are often misdiagnosed. We herewith report a case of linear porokeratosis of Mibelli in
Laxmisha Chandrashekar, Thappa Devinder Mohan, Karthikeyan Kaliaperumal, Jayanthi S   +3 more
doaj  

Giant inflammatory linear verrucous epidermal nevus: Successfully treated with full thickness excision and skin grafting

Indian Journal of Dermatology, 2013
Inflammatory linear verrucous epidermal nevus (ILVEN) is a pruritic, erythematous scaly epidermal nevus which follows a Blaschko′s lines. Lichen striatus, linear Darier disease, linear porokeratosis, linear lichen planus, linear psoriasis, and the ...
Binodini Behera, Basanti Devi, Bibhuti B Nayak, Bharti Sahu, Bhabani Singh, Manas R Puhan   +5 more
doaj   +1 more source

Applicability of Novel Laser Scanning Microscopy Techniques in Demonstrating Characteristic Features of Porokeratosis: In Vivo and Ex Vivo Investigation

JEADV Clinical Practice, Volume 5, Issue 1, Page 91-100, March 2026.
Porokeratoses, used here as an example of keratinization disorders, are marked by cornoid lamella and linked to skin cancer risk, making accurate diagnosis essential. This study compared conventional methods, dermoscopy, and histopathology, with advanced imaging using reflectance confocal microscopy (RCM) and multiphoton microscopy (MPM).
Rahime Inci, Noora Neittaanmäki, Jeemol James, Marica B. Ericson, Sirkku Peltonen, Despoina Kantere   +5 more
wiley   +1 more source

Generalized Linear Porokeratosis in a Child: Case Study

Вопросы современной педиатрии
Background. Linear porokeratosis is a rare type of poroceratosis, genetically determined disorder of mevalonate pathway in keratinocytes. It is characterized by high risk of malignant neoplasms (squamous cell carcinoma, basal cell carcinoma, Bowen's ...
Nikolay N. Murashkin, Leonid A. Opryatin, Anastasiya D. Eremeeva, Natalya L. Sycheva, Ekaterina S. Pavlova, Roman V. Epishev, Alexandr I. Materikin, Mariya A. Leonov, Roman A. Ivanov, Sofya A. Boriskina   +9 more
doaj   +1 more source