Results 41 to 50 of about 685 (153)

Off‐Label Use of Selective JAK1 Inhibitors in Immune‐Mediated Inflammatory Skin Diseases: A Retrospective Case Series

open access: yesDermatologic Therapy, Volume 2026, Issue 1, 2026.
This article aimed to evaluate the efficacy and safety of JAK1 inhibitors (abrocitinib and upadacitinib) in off‐label treatment of refractory inflammatory skin diseases. We retrospectively analyzed 19 patients with various immune‐mediated dermatoses, including cutaneous lichen planus, parapsoriasis, vitiligo, autoimmune bullous diseases ...
Si Zhang   +5 more
wiley   +1 more source

Molecular characterization and natural history of linear porokeratosis: a case series

open access: yes, 2020
Here we employed immunohistochemistry and genetic testing by whole-exome or Sanger sequencing, to characterize six cases with linear porokeratosis (LP), all having negative family history for porokeratosis (Table 1).
saleva, M (via Mendeley Data)
core   +1 more source

Efficacy and Safety of Topical Statin Therapy for Porokeratosis: A Systematic Review and Meta‐Analysis

open access: yesDermatologic Therapy, Volume 2026, Issue 1, 2026.
Background and Objective Porokeratosis comprises a heterogeneous group of keratinization disorders with malignant transformation potential. While multiple therapeutic options exist, clinical outcomes remain suboptimal. Emerging evidence suggests promising efficacy of topical statin therapy, though systematic evaluation is currently lacking.
Xingyu Li   +3 more
wiley   +1 more source

Porokeratosis ptychotropica: a rare case report with unusual presentation

open access: yes, 2018
Porokeratosis is a rare disorder of epidermal keratinization characterized clinically by annular plaque with thread like hyperkeratotic border with a central groove that expand centrifugally and this border corresponds to coronoid lamellae histologically
N., Azeem Jaffer   +2 more
core   +1 more source

Successful Treatment of Plantar Mosaic Warts With Intralesional Bleomycin: A Case Report and Review of Literature

open access: yesClinical Case Reports, Volume 13, Issue 11, November 2025.
ABSTRACT Intralesional bleomycin is an effective and safe treatment option for plantar mosaic warts that are resistant to conventional therapies. This case highlights the importance of targeted intralesional therapy, even in recalcitrant and extensive plantar wart variants, with rapid resolution observed after just two treatment sessions and no ...
Amrit Neupane   +3 more
wiley   +1 more source

Genetic Testing in Mosaicism

open access: yesJEADV Clinical Practice, Volume 4, Issue 3, Page 664-668, August 2025.
ABSTRACT Mosaicism due to postzygotic mutations is more common than considered before the era of massive parallel sequencing. In the clinical dermatologic practice, it is important to recognize skin lesions and syndromes caused by genetic mosaicism, to initiate genetic testing and counsel the patient and families regarding prognosis and risk of ...
Cristina Has
wiley   +1 more source

A Long‐Standing Palmar Depressed Macule

open access: yes
JEADV Clinical Practice, Volume 5, Issue 2, Page 734-736, June 2026.
Jhon Edwin Rodríguez‐Vásquez   +4 more
wiley   +1 more source

Categories of Cutaneous Mosaicism

open access: yesJEADV Clinical Practice, Volume 4, Issue 3, Page 652-658, August 2025.
ABSTRACT In this overview, the following 12 different categories of cutaneous mosaicism are considered: (1) Discrimination between monoallelic and biallelic mosaicism in autosomal dominant traits; (2) Segmental versus disseminated mosaicism in autosomal dominant disorders.
Rudolf Happle
wiley   +1 more source

Linear porokeratosis: a case report [PDF]

open access: yesSerbian Journal of Dermatology and Venerology, 2012
Abstract Porokeratosis is a rare genodermatosis based on chronic keratinization disorder histologically characterized by the presence of a cornoid lamella and various clinical manifestations. Five most commonly described types of poroketarosis are porokeratosis of Mibelli or ”classic” porokeratosis, disseminated superfi cial actinic porokeratosis,
Slobodan Stojanović   +3 more
openaire   +1 more source

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