Results 61 to 70 of about 239,750 (290)
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Techniques for The Regeneration of Wideband Speech from Narrowband Speech
EURASIP Journal on Advances in Signal Processing, 2001 This paper addresses the problem of reconstructing wideband speech signals from observed narrowband speech signals. The goal of this work is to improve the perceived quality of speech signals which have been transmitted through narrowband channels or ...
Gardner William R +2 more
doaj +1 more source
Energies, 2018 Conventional photoplesthymograph (PPG) measurements for heart rate (HR) determination require direct contact between the patient and the PPG device sensor. When using the conventional method, it is possible for users to suffer undesirable skin irritation,
Iman Rahmansyah Tayibnapis +2 more
doaj +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Sistem Pengenalan Kata Dengan Menggunakan Linear Predictive Coding Dan Nearest Neighbor Classifier [PDF]
, 2005 This paper describe about the development of word recognition system by using a voice matching approach, which will match between reference voice spectrum and unknown voice spectrum.
Saputra, H. (Hadi), Thiang, T. (Thiang)
core
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
Aggressive prostate cancer is associated with pericyte dysfunction
Molecular Oncology, EarlyView.Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero +11 more
wiley +1 more source
Pattern recognition applying LDA and LR to optoelectronic signals of optical scanning systems
Revista Iberoamericana de Automática e Informática Industrial RIAI, 2020 This paper is a follow-up to previous researches already published regarding the minimization of optical-electrical noise in optical scanning systems OSS, by the implementation of computational techniques for pattern recognition generated by each ...
J. E. Miranda-Vega +5 more
doaj +1 more source