Results 101 to 110 of about 1,009,619 (268)

Modeling Operation Problem of Micro-grids Considering Economical, Technical and Environmental issues as Mixed-Integer Non-Linear Programming [PDF]

, 2016
Samira Salahi, Salah Bahramara
openalex   +1 more source

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

Cell density–dependent nuclear‐cytoplasmic shuttling of SETDB1 integrates with Hippo signaling to regulate YAP1‐mediated transcription

FEBS Letters, EarlyView.
At low cell density, SETDB1 and YAP1 accumulate in the nucleus. As cell density increases, the Hippo pathway is gradually activated, and SETDB1 is associated with increased YAP1 phosphorylation. At high cell density, phosphorylated YAP1 is sequestered in the cytoplasm, while SETDB1 becomes polyubiquitinated and degraded by the ubiquitin–proteasome ...
Jaemin Eom, Jaewoong Jang, Jung Sun Park, Yong‐Kook Kang   +3 more
wiley   +1 more source

Goal Programming Models with Linear and Exponential Fuzzy Preference Relations [PDF]

, 2020
Mohammad Faisal Khan, Md. Gulzarul Hasan, Abdul Quddoos, Armin Fügenschuh, S. Suhaib Hasan   +4 more
openalex   +1 more source

MIXED-INTEGER LINEAR PROGRAMMING-BASED TRANSMISSION NETWORK EXPANSION PLANNING CONSIDERING POWER LOSS [PDF]

, 2023
Nguyễn Tuấn Anh, Đàm Minh Quang, Phạm Năng Văn   +2 more
openalex   +1 more source

Finding a Feasible Solution for a Simple LP Problem using Agents [PDF]

In this paper we will describe a Multi-Agent System which is capable of finding a feasible solution of a specially structured linear programming problem.
Bruin, A. de, Kindervater, G.A.P., Vredeveld, T., Wagelmans, A.P.M.   +3 more
core   +1 more source

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

Molecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero, Alejandro Belmonte‐Fernández, Mónica González‐Moreno, Laura Rodríguez‐Cordero, Begoña Pérez‐Valderrama, Joaquín Herrero‐Ruíz, Francisco Romero, Carmen Sáez, Miguel Á. Japón   +8 more
wiley   +1 more source

A Global Optimization Algorithm for Sum of Linear Ratios Problem

Journal of Applied Mathematics, 2013
We equivalently transform the sum of linear ratios programming problem into bilinear programming problem, then by using the linear characteristics of convex envelope and concave envelope of double variables product function, linear relaxation programming
Yuelin Gao, Siqiao Jin
doaj   +1 more source

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

Molecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou, Zhen Wang, Fei Yang, Xiao Han, Lei Li, Huadong Liu   +5 more
wiley   +1 more source

Extension of Wolfe Method for Solving Quadratic Programming with Interval Coefficients

Journal of Applied Mathematics, 2017
Quadratic programming with interval coefficients developed to overcome cases in classic quadratic programming where the coefficient value is unknown and must be estimated. This paper discusses the extension of Wolfe method.
Syaripuddin, Herry Suprajitno, Fatmawati
doaj   +1 more source