Results 111 to 120 of about 4,002,335 (287)

Prospecting the protein design landscape

open access: yesFEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona   +4 more
wiley   +1 more source

Hybrid linear programming to estimate CAP impacts of flatter rates and environmental top-ups [PDF]

open access: yes
This paper examines evolutions of the Common Agricultural Policy (CAP) decoupling regime and their impacts on Greek arable agriculture. Policy analysis is performed by using mathematical programming tools.
Stelios Rozakis
core  

An Outline of Linear Programming

open access: yesJournal of the Royal Statistical Society Series B: Statistical Methodology, 1955
Summary Linear Programming is defined and examples of its applications are given. Methods are indicated for the solution.
openaire   +2 more sources

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

open access: yesFEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil   +3 more
wiley   +1 more source

RNA‐related functions of BRCA2 in transcription, replication, and genome stability

open access: yesFEBS Letters, EarlyView.
Beyond its role in homologous recombination, BRCA2 regulates R‐loop homeostasis, DNA–RNA hybrid resolution, RNA polymerase II dynamics, and transcriptional activation. Disruption of any of these functions can contribute to genome instability, inflammatory signaling, and tumorigenesis. BRCA2 is a central tumor suppressor protein best known for its roles
Lucia Alvaro‐Aranda   +2 more
wiley   +1 more source

Repeated patterns in tree genetic programming [PDF]

open access: yes, 2005
We extend our analysis of repetitive patterns found in genetic programming genomes to tree based GP. As in linear GP, repetitive patterns are present in large numbers.
Banzhaf, W., Langdon, W.B.
core  

The Problem of Planning Neutrosophic Hydropower Systems (Converting Some Nonlinear Neutrosophic Models into Linear Neutrosophic Models)

open access: yesNeutrosophic Sets and Systems
The core of operations research activity focuses on creating and using models. These models may be linear models, non-linear models, dynamic models, and others.
Maissam Jdid
doaj   +1 more source

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

open access: yesFEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux   +7 more
wiley   +1 more source

The ubiquitin system in normal and infected germinal center B cells

open access: yesFEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis   +2 more
wiley   +1 more source

Locally Ideal Formulations for Piecewise Linear Functions with Indicator Variables [PDF]

open access: yes, 2013
In this paper, we consider mixed integer linear programming (MIP) formulations for piecewise linear functions (PLFs) that are evaluated when an indicator variable is turned on.
Linderoth, Jeff   +6 more
core  

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