Results 171 to 180 of about 989,620 (282)

Optimization of a Food List for Food Frequency Questionnaires Using Mixed Integer Linear Programming: A Proof of Concept Based on Data from the Second German National Nutrition Survey. [PDF]

Nutrients, 2023
Blaurock J, Heuer T, Gedrich K.
europepmc   +1 more source

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

FEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada, Mina Iwaki, Kyosuke Hagiri, Rei Izumi, Masahiko Harata, Chihiro Horigome   +5 more
wiley   +1 more source

An optimization protocol for MRI examination resource allocation based on demand forecasting and linear programming. [PDF]

Sci Rep
Zhou Z, Zhou H, Qiao Y, Gao Z, Yang Y.
europepmc   +1 more source

Corrigendum: A Review of the Use of Linear Programming to Optimize Diets, Nutritiously, Economically and Environmentally. [PDF]

Front Nutr, 2022
García-Leal J, Espinoza Pérez AT, van Dooren C, Vásquez ÓC.   +3 more
europepmc   +1 more source

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

FEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida, Kazuya Kusama, Ayaka Horiuchi, Yu Kawaguchi, Atsuya Tsuru, Mikihiro Yoshie, Kazuhiro Tamura   +6 more
wiley   +1 more source

Linear programming-based stabilization and synchronization of positive complex networks with dynamic link subsystems. [PDF]

PLoS One
Hong S, Zhang J, Zheng G, Yang H, Uzair Aslam B.   +4 more
europepmc   +1 more source

Anchorage‐independent and faster growth in clonal population from UV‐irradiated NER‐deficient cells

FEBS Open Bio, EarlyView.
UV‐irradiated cells expressing a DDB2 mutant protein unable to interact with PCNA (DDB2PCNA‐) form clones able to grow without anchorage. Different experimental approaches reveal heterogeneity in cell cycle regulation and drug response within these clones, emphasizing the crucial role of the DDB2‐PCNA interaction in preventing cellular transformation ...
Paola Perucca, Anna Tricarico, Martina Furfaro, Priyam Ghosh, Ennio Prosperi, Lucia Anna Stivala, Ornella Cazzalini   +6 more
wiley   +1 more source

A mixed-integer linear programming method for time-dependent line planning in passenger railway systems. [PDF]

PLoS One
Shi X, Zhou W, Li X.
europepmc   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

A New Ant Colony Optimization-Based Dynamic Path Planning and Energy Optimization Model in Wireless Sensor Networks for Mobile Sink by Using Mixed-Integer Linear Programming. [PDF]

Biomimetics (Basel)
Chen F, Wu X, Wang Z, Qi W, Li P.
europepmc   +1 more source