Results 71 to 80 of about 3,251,267 (306)
Unraveling LINE‐1 retrotransposition in head and neck squamous cell carcinoma
Molecular Oncology, EarlyView.The novel RetroTest method allows the detection of L1 activation in clinical samples with low DNA input, providing global L1 activity and the identification of the L1 source element. We applied RetroTest to a real‐world cohort of HNSCC patients where we reported an early L1 activation, with more than 60% of T1 patients showing L1 activity.
Jenifer Brea‐Iglesias +12 more
wiley +1 more source
Sublinear expectation linear regression [PDF]
, 2013 Nonlinear expectation, including sublinear expectation as its special case, is a new and original framework of probability theory and has potential applications in some scientific fields, especially in finance risk measure and management.
Lin, Lu +3 more
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Molecular Oncology, EarlyView.Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley +1 more source
Imputing missing values using cumulative linear regression
CAAI Transactions on Intelligence Technology, 2019 The concept of missing data is important to apply statistical methods on the dataset. Statisticians and researchers may end up to an inaccurate illation about the data if the missing data are not handled properly.
Samih M. Mostafa
doaj +1 more source
Molecular Oncology, EarlyView.Analysis of treatment‐naïve high‐grade serous ovarian carcinoma (HGSOC) and control tissues for ERVs, LINE‐1 (L1), inflammation, and immune checkpoints identified five clusters with diverse patient recurrence‐free survivals. An inflammation score was calculated and correlated with retroelement expression, where one novel cluster (Triple‐I) with high ...
Laura Glossner +6 more
wiley +1 more source
American Journal of Orthodontics and Dentofacial Orthopedics, 2016 Christian Heumann +2 more
openaire +3 more sources
Molecular Oncology, EarlyView.Human cytomegalovirus infection is common in normal prostate epithelium, prostate tumor tissue, and prostate cancer cell lines. CMV promotes cell survival, proliferation, and androgen receptor signaling. Anti‐CMV pharmaceutical compounds in clinical use inhibited cell expansion in prostate cancer models in vitro and in vivo, motivating investigation ...
Johanna Classon +13 more
wiley +1 more source
Piecewise Linear Regression Based on Plane Clustering
IEEE Access, 2019 Piecewise linear regressions have shown many successful applications in image denoising, signal process, and data mining fields. In essence, they attempt to seek multiple linear functions (piecewise/stepwise function) to fit the given scatter data points
Xubing Yang +6 more
doaj +1 more source
Linear Regression Diagnostics [PDF]
This paper attempts to provide the user of linear multiple regression with a battery of diagnostic tools to determine which, if any, data points have high leverage or influence on the estimation process and how these possibly discrepant data points ...
Edwin Kuh, Roy E. Welsch
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