Results 111 to 120 of about 910,585 (293)

Holistic Generalized Linear Models

Journal of Statistical Software
Holistic linear regression extends the classical best subset selection problem by adding additional constraints designed to improve the model quality.
Benjamin Schwendinger, Florian Schwendinger, Laura Vana   +2 more
doaj   +1 more source

Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity

FEBS Open Bio, EarlyView.
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz, Bruna Abreu, Cindy Mendes, Catarina Freitas‐Dias, Filipe Gonçalves, Fernanda Silva, José Ramalho, Saudade André, Vasco D. B. Bonifácio, Jacinta Serpa   +9 more
wiley   +1 more source

Mixing Frequencies : Stock Returns as a Predictor of Real Output Growth [PDF]

We investigate two methods for using daily stock returns to forecast, and update forecasts of, quarterly real output growth. Both methods aggregate daily returns in some manner to form a single stock market variable.
Anthony S. Tay
core   +1 more source

DDX3X induces mesenchymal transition of endothelial cells by disrupting BMPR2 signaling

FEBS Open Bio, EarlyView.
Elevated DDX3X expression led to downregulation of BMPR2, a key regulator of endothelial homeostasis and function. Our co‐immunoprecipitation assays further demonstrated a molecular interaction between DDX3X and BMPR2. Notably, DDX3X promoted lysosomal degradation of BMPR2, thereby impairing its downstream signaling and facilitating endothelial‐to ...
Yu Zhang, Jing Wang, De‐Hui Qian, Yang‐Fan Lv, Tian‐Le Cheng, Da‐Peng Wang, Jing Zhang, Ye Fan   +7 more
wiley   +1 more source

PEMODELAN PERSENTASE PENDUDUK MISKIN DI KABUPATEN DAN KOTA DI JAWA TENGAH DENGAN PENDEKATAN MIXED GEOGRAPHICALLY WEIGHTED REGRESSION [PDF]

, 2014
Regression analysis is a statistical analysis that models the relationship between the response variable and the predictor variable. Geographically Weighted Regression (GWR) is the development of linear regression with the added factor of the ...
Hakim, Arief Rachman
core  

Comparing regression estimation techniques when predicting diameter distributions of Scots pine on drained peatlands

Silva Fennica, 2007
We compared different statistical methods for fitting linear regression models to a longitudinal data of breast height diameter (dbh) distributions of Scots pine dominated stands on drained peatlands.
Siipilehto, Jouni, Sarkkola, Sakari, Mehtätalo, Lauri   +2 more
doaj   +1 more source

TMC4 localizes to multiple taste cell types in the mouse taste papillae

FEBS Open Bio, EarlyView.
Transmembrane channel‐like 4 (TMC4), a voltage‐dependent chloride channel, plays a critical role in amiloride‐insensitive salty taste transduction. TMC4 is broadly expressed in all mature taste cell types, suggesting a possible involvement of multiple cell types in this pathway.
Momo Murata, Yoshikazu Saito, Yoichi Kasahara, Wataru Fujii, Takumi Misaka, Tomiko Asakura, Masataka Narukawa   +6 more
wiley   +1 more source

S-estimation and a robust conditional Akaike information criterion for linear mixed models. [PDF]

We study estimation and model selection on both the fixed and the random effects in the setting of linear mixed models using outlier robust S-estimators.
Claeskens, Gerda, Tharmaratnam, Kukatharmini   +1 more
core  

Comparison of height-diameter models based on geographically weighted regressions and linear mixed modelling applied to large scale forest inventory data

Forest Systems, 2016
Aim of the study: The main objective of this study was to test Geographically Weighted Regression (GWR) for developing height-diameter curves for forests on a large scale and to compare it with Linear Mixed Models (LMM).
María Quirós Segovia, Sonia Condés Ruiz, Karel Drápela   +2 more
doaj   +1 more source

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

FEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu, Hao Jiang, Limin Chen, Fulai Zhou, Ying Jin, Mark L. Chiu   +5 more
wiley   +1 more source