Results 111 to 120 of about 2,688,321 (280)

Intrinsic Functional Partially Linear Poisson Regression Model for Count Data

Axioms
Poisson regression is a statistical method specifically designed for analyzing count data. Considering the case where the functional and vector-valued covariates exhibit a linear relationship with the log-transformed Poisson mean, while the covariates in
Jiaqi Xu, Yu Lu, Yuanshen Su, Tao Liu, Yunfei Qi, Wu Xie   +5 more
doaj   +1 more source

Combined 5‐aminolevulinic acid and ferric ammonium citrate treatment promotes hair follicle growth by activating dermal papilla cells

FEBS Open Bio, EarlyView.
5‐Aminolevulinic acid combined with ferric ammonium citrate (5‐ALA/FAC) stimulates dermal papilla cell activity and promotes hair follicle growth. The treatment enhances ERK and AKT signaling, increases hair‐inductive gene expression, and restores dermal papilla function suppressed by dihydrotestosterone and oxidative stress, resulting in enhanced hair
Han‐Wook Ryu, Eok‐Soo Oh, Sewoon Kim
wiley   +1 more source

On the mixed Kibria-Lukman estimator for the linear regression model. [PDF]

Sci Rep, 2022
Chen H, Wu J.
europepmc   +1 more source

Smoothing Estimation of Parameters in Censored Quantile Linear Regression Model

Mathematics
In this paper, we propose a smoothing estimation method for censored quantile regression models. The method associates the convolutional smoothing estimation with the loss function, which is quadratically derivable and globally convex by using a non ...
Mingquan Wang, Xiaohua Ma, Xinrui Wang, Jun Wang, Xiuqing Zhou, Qibing Gao   +5 more
doaj   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Multivariate linear regression model based on cross-entropy for estimating disorganisation in drone formations. [PDF]

Sci Rep, 2023
Gackowska M, Cofta P, Śrutek M, Marciniak B.   +3 more
europepmc   +1 more source

A Piecewise Linear Regression Model Ensemble for Large-Scale Curve Fitting

Algorithms
The Linear Hinges Model (LHM) is an efficient approach to flexible and robust one-dimensional curve fitting under stringent high-noise conditions. However, it was initially designed to run in a single-core processor, accessing the whole input dataset ...
Santiago Moreno-Carbonell, Eugenio F. Sánchez-Úbeda   +1 more
doaj   +1 more source

Identifying gene expression signatures for risk stratification of postoperative adjuvant chemotherapy in colorectal cancer

FEBS Open Bio, EarlyView.
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo, Keisuke Okuno, Shuichi Watanabe, Sakiko Oba, Hiroyasu Kagawa, Masanori Tokunaga, Daisuke Ban, Yusuke Kinugasa   +7 more
wiley   +1 more source

Bayesian Quantile Regression for Partial Functional Linear Spatial Autoregressive Model

Axioms
When performing Bayesian modeling on functional data, the assumption of normality is often made on the model error and thus the results may be sensitive to outliers and/or heavy tailed data.
Dengke Xu, Shiqi Ke, Jun Dong, Ruiqin Tian   +3 more
doaj   +1 more source

Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment

Aging and Cancer, EarlyView.
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey, Murilo Ramos Rocha, Cheyenne Palm, Vania Wang, Denys Balandin, Ethan Black, Kevin Y. Zhang, Fan Huang, Daniel J. Zabransky, Yash Chhabra, Mareike Peters, Gabriel Ghiaur, Ashani Weeraratna   +12 more
wiley   +1 more source