Results 141 to 150 of about 9,853 (229)

Ribosomal Proteins in Cell Biology and Cancer

open access: yesMedComm – Oncology, Volume 5, Issue 2, June 2026.
The functions of ribosomal proteins (RPs) extend beyond the conventional translation process, as they also regulate gene expression, stress responses, and disease progression. Dysregulation of RPs contributes to the onset and progression of various diseases, including cancer and ribosomopathies, underscoring their dual role as critical disease ...
Ao Zhang   +4 more
wiley   +1 more source

Activity‐Based Functional Exercise for Disability in Systemic Sclerosis: Protocol for a Feasibility Randomised Controlled Trial

open access: yesMusculoskeletal Care, Volume 24, Issue 2, June 2026.
ABSTRACT Introduction Systemic Sclerosis (SSc) is associated with substantial disability in affected patients. Although exercise interventions for SSc have been developed, most focus on isolated body segments rather than global disability. Thus, this study aims to assess the feasibility of a functional activity‐based exercise programme designed to ...
Gabriela da Silva Santos   +7 more
wiley   +1 more source

Loss of Brain‐Derived Estrogen Is Associated With Sex‐ and Age‐Dependent Alterations in Memory, Affective Behavior, and Hippocampal Extracellular Matrix Gene Expression

open access: yesAging Cell, Volume 25, Issue 6, June 2026.
Age, sex, and estrogen loss are widely recognized risk factors for Alzheimer's disease. Here, we show that brain‐specific aromatase knockout (bArKO) and the resulting estrogen loss lead to memory impairment, reduced social interaction, and extracellular environment dysregulation selectively in aged female mice, but not in young female or male mice ...
Natalie C. Piehl   +12 more
wiley   +1 more source

High frequency of CD95+/CD45RA− regulatory T cells defines an immunosuppressive profile associated with MDS progression

open access: yesBritish Journal of Haematology, Volume 208, Issue 6, Page 1993-2003, June 2026.
Summary Dynamic interactions between mutated haematopoietic cells and immune cells are key drivers of myelodysplastic neoplasms (MDS) initiation and progression. Regulatory T cells (Tregs) are central mediators of immunosuppression in MDS. We thus aimed to characterize Treg subpopulations in the bone marrow (BM) of MDS patients and to explore their ...
Romain Vazquez   +18 more
wiley   +1 more source

Post‐Inflammatory Hyperpigmentation: Molecular Mechanisms and Advances in Dermocosmetic Management

open access: yesJournal of Cosmetic Dermatology, Volume 25, Issue 6, June 2026.
ABSTRACT Background Post‐inflammatory hyperpigmentation (PIH) is a condition that causes skin pigmentation after acute or chronic inflammation. It affects people with darker skin tones more than others, especially Asians (Fitzpatrick types III–VI), and can last for months or even years, making life much less enjoyable.
Rui Li   +10 more
wiley   +1 more source

Congenital localized scleroderma

open access: yes
Objectives Juvenile localized scleroderma (JLS) usually has its onset during later childhood. This report describes the clinical and serologic features of six children with congenital localized scleroderma (CLS).
Zulian , F.
core  

Long-term follow-up of linear scleroderma en coup de sabre in children with central nervous system involvement. [PDF]

open access: yesFront Immunol
Chang X   +8 more
europepmc   +1 more source

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