Results 71 to 80 of about 6,691 (217)

Multi‐omic analysis identifies biological processes underlying progressive interstitial lung disease in systemic sclerosis

The FEBS Journal, EarlyView.
Systemic sclerosis (SSc) is a rare autoimmune disease, and lung complications (ILD) are the main cause of death. This study compared SSc patients with and without lung disease to healthy volunteers. We found increased inflammation, specific proteins, and higher triglyceride levels linked to lung disease progression. These findings suggest triglycerides
Selena Bouffette, Perrine Soret, Alice Cole, Emmanuel Nony, Pierre Barbier Saint Hilaire, Grégory Leclerc, Lamine Alaoui, Audrey Aussy, Isabelle Wehrle, Aude Le Gall, Mark Coulon, Marc Pallardy, Voon Ong, Jeanne Allinne, Philippe Moingeon, David Abraham, Christopher P. Denton   +16 more
wiley   +1 more source

Sketching T cell atlases in the single‐cell era: challenges and recommendations

Immunology &Cell Biology, EarlyView.
Recent advances in single‐cell technologies have enabled the creation of T cell atlases, providing detailed maps of adaptive immunity across tissues, development and disease states. These atlases help uncover T cell diversity, functional states and disease mechanisms, aiding in the identification of therapeutic targets.
Itana Bojović, António GG Sousa, Sini Junttila, Laura L Elo   +3 more
wiley   +1 more source

Periodontitis and Periodontal Conditions in Systemically Healthy Children and Adolescents

Journal of Clinical Periodontology, EarlyView.
ABSTRACT Objective To answer the PICoS question ‘in systemically healthy children and adolescents (Population), what are the main features of periodontitis, necrotising periodontal diseases (NPD) and other periodontal conditions (periodontal abscesses, endo‐periodontal lesions, traumatic occlusal forces, prosthesis‐ and tooth‐related factors ...
Inbar Eshkol‐Yogev, Nagore Ambrosio, Cheryl Somani, Elena Figuero, Lior Shapira, Janet Davies   +5 more
wiley   +1 more source

Erectile dysfunction in dermatology and venereology: From aetiopathogenic mechanisms to practical considerations for dermato‐venereologists

Journal of the European Academy of Dermatology and Venereology, EarlyView.
Multiple inflammatory, infectious and autoimmune dermato‐venereological conditions are associated with erectile dysfunction (ED) due to underlying intricate vasculogenic, neurogenic, endocrine and psychogenic mechanisms. It is recommended that practitioners screen dermatology patients for ED and associated comorbidities, provide personalized lifestyle ...
Andrei Tanasov, George‐Sorin Tiplica
wiley   +1 more source

Localized scleroderma – classification and tools used for the evaluation of tissue damage and disease activity/severity

Przegląd Dermatologiczny, 2017
Localized scleroderma is a rare autoimmune disorder affecting the dermis, subcutaneous tissue and deeper structures. The course of localized scleroderma includes three stages: early inflammation, progressive sclerosis and atrophy. The active stage of the
Katarzyna Wolska-Gawron, Dorota Krasowska   +1 more
doaj   +1 more source

Assessment of Esophagogastric Junction Barrier Function With the Supine‐Upright Transition of the Chicago Classification Protocol

Neurogastroenterology &Motility, EarlyView.
ABSTRACT Background & Aims The straight leg raise (SLR) is a provocative maneuver used to assess the esophagogastric junction (EGJ) barrier function during high‐resolution manometry (HRM) and is part of the Milan Score (MS). The Chicago Classification 4.0 (CCv4.0) protocol requires patients to perform a supine‐upright transition (SUT), increasing intra‐
Stefano Siboni, Roberta De Maron, Andrea Pasta, Marco Sozzi, Francesco Calabrese, Pierfrancesco Visaggi, Nicola De Bortoli, Anthony Hobson, Jordan Haworth, Daniele Bernardi, Takahiro Masuda, Giovanni Aldinio, Marina Coletta, Roberto Penagini, Edoardo Savarino, Emanuele Asti, C. Prakash Gyawali, Elisa Marabotto   +17 more
wiley   +1 more source

Optimizing the Straight Leg Raise Maneuver to Improve Prediction of Conclusive Gastro‐Esophageal Reflux Disease

Neurogastroenterology &Motility, EarlyView.
The SLR maneuver is a valuable component of GERD evaluation. By establishing optimal thresholds for both effective EGJ challenge and accurate GERD prediction, we provide another step for standardized implementation in clinical practice. ABSTRACT Background Gastroesophageal reflux disease (GERD) arises from dysfunction of the anti‐reflux barrier.
Stefano Siboni, Carlo Galdino Riva, Roberta De Maron, Marco Sozzi, Pierfrancesco Visaggi, Edoardo Savarino, Emanuele Asti, C. Prakash Gyawali   +7 more
wiley   +1 more source

Extracutaneous Lesions in Patients with Focal Scleroderma of Craniofacial Localization: a Retrospective Cross-Sectional Study

Вопросы современной педиатрии
Background. Focal scleroderma is rare, acquired disease characterized by inflammation, sclerosis, skin and underlying tissues atrophy, with no lesions to internal organs.
Nikolay N. Murashkin, Alexander I. Materikin, Roman V. Epishev, Maria A. Leonova, Leonid A. Opryatin, Dmitry V. Fedorov, Roman A. Ivanov, Alena A. Savelova, Ekaterina S. Pavlova, Anastasiya U. Ufimtseva   +9 more
doaj   +1 more source

A case report of Parry–Romberg syndrome

Clinical Case Reports
Key Clinical Message Parry–Romberg syndrome is characterized by progressive dystrophy in one half of the face, which usually begins in childhood. Correct and timely diagnosis of this disease, as well as a multidisciplinary approach and timely surgical ...
Kiana Babaei, Ali Rahnama, Nora Shurvarzi, Ali Movahedi   +3 more
doaj   +1 more source

Living in the Mycelial World

Topics in Cognitive Science, EarlyView.
Abstract This manuscript documents a systematic ethnomycological analysis of ethnographic archives. Focusing on texts describing human–fungi interactions, I conduct a global, cross‐cultural review of mushroom use, covering 193 societies worldwide. The study reveals diverse mushroom‐related cultural practices, emphasizing the significance of fungi ...
Roope O. Kaaronen
wiley   +1 more source