Results 21 to 30 of about 10,224 (255)

The solvent effect, preferential solvation of metformin hydrochloride in binary mixed solvents of methanol/ethanol + water mixtures from 278.15 K to 323.15 K

South African Journal of Chemical Engineering
This study provides a novel quantitative analysis of metformin hydrochloride (MET-HCl) solvation behavior in binary solvents mixtures of methyl alcohol and water, as well as ethyl alcohol and water, addressing critical gaps in understanding its ...
Adel Noubigh, Abdalazeem A. Omar, Manef Abderrabba   +2 more
doaj   +1 more source

Computational study on the effects of solvent and thermodynamic properties of the pharmaceutical compound milrinone in aqueous solutions of ethanol and 2-propanol

Chemical Thermodynamics and Thermal Analysis
In this study, the Kamlet–Abboud–Taft linear solvation energy relationship (KAT-LSER) model, van't Hoff analysis, and Inverse Kirkwood-Buff Integrals method were applied to determine solvent effects, dissolution thermodynamics, and preferential solvation
Adel Noubigh, Mustafa Jaipallah Abualreish, Manef Abderrabba   +2 more
doaj   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Synthesis of a new organic probe 4-(4 acetamidophenylazo) pyrogallol for spectrophotometric determination of Bi(III) and Al(III) in pharmaceutical samples

Reviews in Analytical Chemistry, 2021
A modern development discusses the synthesis and validity of simple, sensitive, and versatile spectrophotometric methods for Bi(III) and Al(III) determination in pharmaceutical formulations have been conducted.
Ammar Jumana W., Khan Zainab A., Ghazi Marwa N., Naser Naser A.   +3 more
doaj   +1 more source

Modeling headspace solid-phase microextraction of volatile organic compounds from water samples with porous coatings using finite element analysis

Advances in Sample Preparation, 2022
This research was aimed at the development of the COMSOL Multiphysics® (CMP) model for simulating the headspace (HS) solid-phase microextraction (SPME) of volatile organic compounds (VOCs) from water using Carboxen/polydimethylsiloxane coating at 25 °C ...
Aset Muratuly, Anel Kapar, Bulat Kenessov   +2 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Solvent effect on protonation of tpps in water-DMF mixtures

Bulletin of the Chemical Society of Ethiopia, 2017
The protonation of 5,10,15,20-tetrakis(4-sulfonatophenyl)porphyrin was investigated in aqueous solutions of N,N-dimethyformamide at 25 °C and 0.1 mol.dm-3 sodium perchlorate.
A. Farajtabar, M. Faeli
doaj   +1 more source

Revisiting the Total Hildebrand and Partial Hansen Solubility Parameters of Analgesic Drug Meloxicam

Liquids, 2023
The reported total Hildebrand solubility parameter (δ2) value of meloxicam, as calculated based on the group contribution method proposed by Fedors, was compared with those estimated based on the maximum solubility peaks observed in different aqueous ...
Darío A. Tinjacá, Fleming Martinez, María Angeles Peña, Abolghasem Jouyban, William E. Acree   +4 more
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

A Study on Retention of a Series of Aromatic Compounds in Mixed Micellar Liquid Chromatography Using Linear Solvation Energy Relationship (LSER) [PDF]

Iranian Journal of Chemistry & Chemical Engineering, 2006
The effect of SDS (0.03-0.07 M) and Brij-35(0-0.003 M) concentrations and temperature on retention parameters of 30 solutes in micellar reversed- phase liquid chromatography systems were studied using solvation parameter model.
Mohammad Reza Hadjmohammadi, Mitra Rezaie   +1 more
doaj