Results 31 to 40 of about 10,224 (255)
FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
Journal of Cheminformatics, 2021 The experimental values of skin permeability coefficients, required for dermal exposure assessment, are not readily available for many chemicals. The existing estimation approaches are either less accurate or require many parameters that are not readily ...
Sana Naseem, Yasuyuki Zushi, Deedar Nabi
doaj +1 more source
FEBS Letters, EarlyView.The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson +6 more
wiley +1 more source
linear solvation energy relationships
, 2014 Citation: 'linear solvation energy relationships' in the IUPAC Compendium of Chemical Terminology, 3rd ed.; International Union of Pure and Applied Chemistry; 2006. Online version 3.0.1, 2019. 10.1351/goldbook.L03559 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms.
openaire +1 more source
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Solvatochromism Effect of Different Solvents on UV-Vis Spectra of Flouresceine and its Derivatives [PDF]
Iranian Journal of Chemistry & Chemical Engineering, 2008 The solvatochromism of fluoresceine and its derivatives was studied in solvents of different Hydrogen Bond Donor (HBD), Hydrogen Bond Acceptor (HBA), Donor Number (DN) and Acceptor Number (AN) by their UV-Vis spectra.
Mohammad Reza Hadjmohammadi +2 more
doaj
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Solvatochromism studies on UV spectra of 4,5-disubstituted-1,2,4-triazoline-3-thiones
Macedonian Journal of Chemistry and Chemical Engineering, 2012 The influence of a series of organic solvents on the UV spectra of investigated 1,2,4-triazoles, was studied by implementing solvatochromic theory.
Vesna B. Dimova +1 more
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
AIP Advances, 2020 Among various techniques for treating polybrominated diphenyl ethers (PBDEs), adsorption and removal methods using carbon materials are widely applied to remove and decompose organic pollutants with high efficiency.
Taeyoon Kim, Yongju Kwon, Soonchul Kwon
doaj +1 more source