The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Reaction between linear perfluoroaldehydes and hydroperoxy radical in the atmosphere: reaction mechanisms, reaction kinetics modelling, and atmospheric implications [PDF]
Atmospheric Chemistry and PhysicsLinear perfluoroaldehydes are important products formed in the atmospheric oxidation of industrial fluorinated compounds. However, their atmospheric lifetimes are incompletely known.
Z. Dong, Z. Dong, C. Xie, B. Long
doaj +1 more source
Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers
FEBS Letters, EarlyView.Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui +4 more
wiley +1 more source
FEBS Letters, EarlyView.Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise +5 more
wiley +1 more source
Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research
FEBS Letters, EarlyView.What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley +1 more source
Transit : a story inspired by Melbourne's taxi entrepreneurs from Hadchit, North Lebanon
, 2006 Cover title: Tansa. Exhibition held at Span Galleries from 14-18 November 2006. "TOW is a research and arts practice and undertakes projects centred on the Lebanese migration to Australia"--Cover verso.Bibliography: p ...
Span Galleries
core
Linear maps preserving permutation and stochastic matrices [PDF]
, 2002 Let T be the set of n×n (sub)permutation matrices, doubly (sub)stochastic matrices, or the set of m×n column or row (sub)stochastic matrices. We characterize those linear maps T on the linear span of T that satisfy T(T)=T .
Li, Chi-Kwong +9 more
core +1 more source
A robust numerical method for the generation and propagation of periodic finite-amplitude internal waves in natural waters using high-accuracy simulations [PDF]
Nonlinear Processes in GeophysicsThe design and implementation of boundary conditions for the robust generation and simulation of periodic finite-amplitude internal waves is examined in a quasi two-layer continuous stratification using a spectral-element-method-based incompressible flow
P. Lloret +3 more
doaj +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Molecular Oncology, EarlyView.Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source