Results 61 to 70 of about 3,487,435 (303)

The maturation of reticulocytes. II. Life-span of red cells originating from stress reticulocytes [PDF]

open access: yes, 1975
Life-spans of macroreticuloytes and macrocytic red cells were studied. Rabbits were made anemic by injecting phenylhydrazine. Peripheral blood rich in reticulocytes was drawn, labeled with 3H-amino acids, and injected back into the anemic animal ...
Shimada, Atsuko
core   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Novel electroanalysis of hydroxyurea at glassy carbon and gold electrode surfaces

open access: yesJournal of Electrochemical Science and Engineering, 2014
A simple and a novel electroanalysis of hydroxyurea (HU) drug at glassy carbon and gold electrode was investigated for the first time using cyclic, linear sweep and differential pulse voltammetric techniques.
Keerti M. Naik   +1 more
doaj   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

Stanford Linear Accelerator Center Annual Environmental Monitoring Report, January--December 1989

open access: yes, 1990
This progress report discusses environmental monitoring activities at the Stanford Linear Accelerator Center for 1989. Topics include climate, site geology, site water usage, land use, demography, unusual events or releases, radioactive and ...
Stanford Linear Accelerator Center
core   +1 more source

Noise Reduction with Optimal Variable Span Linear Filters [PDF]

open access: yesIEEE/ACM Transactions on Audio, Speech, and Language Processing, 2016
In this paper, the problem of noise reduction isaddressed as a linear filtering problem in a novel way by usingconcepts from subspace-based enhancement methods, resultingin variable span linear filters. This is done by forming the filtercoefficients as linear combinations of a number of eigenvectorsstemming from a joint diagonalization of the ...
Jesper Rindom Jensen   +2 more
openaire   +2 more sources

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

QSAR Studies of Toxicity Towards Monocytes with (1,3-benzothiazol-2-yl) amino-9-(10H)-acridinone Derivatives Using Electronic Descriptors

open access: yesOrbital: The Electronic Journal of Chemistry, 2015
DFT-B3LYP method, with the basis set 6-31G (d), was employed to calculate nine quantum chemical descriptors of 16 acridin-9-(10H)-ones substituted with amino or (1,3-benzothiazol-2-yl)-amino groups compounds.
Chtita Samir   +4 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

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