Results 61 to 70 of about 200,494 (291)
Under a suitable notion of equivalence of integral densities we prove a $\Gamma$-closure theorem for integral functionals: The limit of a sequence of $\Gamma$-convergent families of such functionals is again a $\Gamma$-convergent family.
Jesenko, Martin, Schmidt, Bernd
core +1 more source
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Linearization of thick K-branes
We study the linearization of a class of thick K-branes, namely, four-dimensional domain walls generated by a scalar field with particular nonstandard kinetic terms. The master equations for linear perturbations are derived from the point of view of both
Liu, Yu-Xiao, Zhong, Yuan
core +1 more source
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
AAA+ protein unfoldases—the Moirai of the proteome
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley +1 more source
Harmonic Balance for Non-Periodic Hyperbolic Solutions of Nonlinear Ordinary Differential Equations
In this paper, we propose a new approach for obtaining explicit analytical approximations to the homoclinic or heteroclinic solutions of a general class of strongly nonlinear ordinary differential equations describing conservative singledegree-of-freedom
Serge Bruno Yamgoue +2 more
doaj +1 more source
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
35 pages, contribution to the CAS - CERN Accelerator School: Advanced Accelerator Physics Course, Trondheim, Norway, 18-29 Aug 2013.
openaire +3 more sources

