Results 71 to 80 of about 58,035 (315)
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Koopman Spectral Linearization vs. Carleman Linearization: A Computational Comparison Study
Nonlinearity presents a significant challenge in problems involving dynamical systems, prompting the exploration of various linearization techniques, including the well-known Carleman Linearization.
Shi, Dongwei, Yang, Xiu
core
FEEDBACK LINEARIZATION OF PIECEWISE LINEAR SYSTEMS [PDF]
One of the classical problems of nonlinear systems and control theory is feedback linearization. Its obvious motivation is that one can utilize linear control theory if the nonlinear system at hand is linearizable by feedback. This problem is well-understood for the smooth nonlinear systems. In the present paper, we investigate feedback linearizability
Çamlıbel, Mehmet Kanat +1 more
openaire +2 more sources
The human gut microbiome across the life course
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source
A comparison of linearization and quadratization domains [PDF]
summary:In a nonlinear model, the linearization and quadratization domains are considered. In the case of a locally quadratic model, explicit expressions for these domains are given and the domains are ...
Kubáček, Lubomír, Jenčová, Anna
core +1 more source
Harmonic Balance for Non-Periodic Hyperbolic Solutions of Nonlinear Ordinary Differential Equations
In this paper, we propose a new approach for obtaining explicit analytical approximations to the homoclinic or heteroclinic solutions of a general class of strongly nonlinear ordinary differential equations describing conservative singledegree-of-freedom
Serge Bruno Yamgoue +2 more
doaj +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Distortion correction of LDMOS power amplifiers using hybrid RF second harmonic injection/digital predistortion linearization [PDF]
An LDMOS RF power amplifier for RF multichannel wireless systems with improved IMD performance characteristics is presented. The application of two combined linearization methods is being tested with the help of circuit simulation software ADS.
Budimir, D., Koulouzis, H.
core +1 more source
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source

