Results 81 to 90 of about 69,329 (303)
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
STATISTICAL LINEARIZATION METHOD OF DUFFING OSCILLATOR UNDER GAUSSIAN WHITE NOISE EXCITATION [PDF]
In this paper is presented a statistical linearization method of Duffing oscillator under Gaussian white noise excitation. Duffing oscillator’s dispersion response to various nonlinearities and spectral intensities is obtained by the statistical ...
Ovidiu Solomon
core
Nonlinear cross Gramians and gradient systems [PDF]
, 2007 We study the notion of cross Gramians for non-linear gradient systems, using the characterization in terms of prolongation and gradient extension associated to the system.
Jacquelien M. A. Scherpen +5 more
core +2 more sources
FEBS Letters, EarlyView.Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
Linearized Implicit Numerical Method for Burgers’ Equation
Nonlinear Engineering, 2016 In this work, a novel numerical scheme based on method of lines (MOL) is proposed to solve the nonlinear time dependent Burgers’ equation. The Burgers’ equation is semi discretized in spatial direction by using MOL to yield system of nonlinear ordinary ...
Mukundan Vijitha, Awasthi Ashish
doaj +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
FEBS Letters, EarlyView.In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
, 2010 This paper presents the linearization of a high-efficiency compressed power amplifier (PA) by iterative digital predistortion with suppression of memory effects.
Budimir, D. +7 more
core +1 more source
Translophagy—A potential link between autophagy impairment and translational errors
FEBS Letters, EarlyView.Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
Multi-Energy Flow Modeling and Optimization of Electric-Gas-Thermal Integrated Energy System
Shanghai Jiaotong Daxue xuebaoIn view of the fact that the conversion of various energy forms such as electricity, gas, and heat in the regional integrated energy system (RIES) seriously affects the economy of the system operation, a mathematical model and an optimization model of ...
LI Bingjie, YUAN Xiaoyun, SHI Jing, XU Huachi, LUO Zixuan
doaj +1 more source