Results 51 to 60 of about 2,364,715 (303)

Covering link calculus and iterated Bing doubles

open access: yes, 2018
We give a new geometric obstruction to the iterated Bing double of a knot being a slice link: for n > 1 the (n+1)-st iterated Bing double of a knot is rationally slice if and only if the n-th iterated Bing double of the knot is rationally slice. The main
Kim, T, Cha, JC
core   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Application of hyperbolic geometry in link prediction of multiplex networks [PDF]

open access: yesScientific Reports, 2019
AbstractRecently multilayer networks are introduced to model real systems. In these models the individuals make connection in multiple layers. Transportation networks, biological systems and social networks are some examples of multilayer networks.
Samei, Zeynab, Jalili, Mahdi
openaire   +2 more sources

Zeta function rigidity : a view from noncommutative geometry [PDF]

open access: yes, 2011
In this thesis we study the zeta function formalism of finitely summable spectral triples in noncommutative geometry introduced by Alain Connes in 1995.
de Jong, J.W.W.   +2 more
core   +1 more source

The Geometry of Conventionality [PDF]

open access: yes, 2013
Hans Reichenbach famously argued that the geometry of spacetime is conventional in relativity theory, in the sense that one can freely choose the spacetime metric so long as one is willing to postulate a "universal force field".
Weatherall, James Owen   +3 more
core   +1 more source

‘Guide and Prejudice’— How Argonautes recognize targets across domains of life

open access: yesFEBS Letters, EarlyView.
Argonaute proteins use short nucleic‐acid guides to locate and regulate specific targets across all domains of life. Despite striking diversity—from human gene silencing to bacterial immune defence—all Argonautes share a conserved three‐stage recognition logic: guide‐directed sampling, progressive target pairing with a conformational checkpoint and ...
Jack P. K. Bravo
wiley   +1 more source

Shape and fluctuations of frustrated self-assembled nano ribbons

open access: yesNature Communications, 2019
Supramolecular assemblies achieve nontrivial structures but there is no general framework to link their formation to molecular properties. Here the authors propose a model that relates molecular geometry and interactions to nanoribbon formation ...
Mingming Zhang   +3 more
doaj   +1 more source

Some aspects of topology and kinematics of a 3DOF translational parallel mechanism

open access: yesInternational Journal of Applied Mechanics and Engineering, 2014
The paper presents elements of the topology, geometry and the kinematic analysis of a translational parallel mechanism with three degrees of freedom.
J. Bałchanowski
doaj   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

THE ROLE OF PROJECTIVE GEOMETRY IN TALIAN EDUCATION AND INSTITUTIONS AT THE END OF THE 19TH CENTURY

open access: yesRevista de História da Educação Matemática, 2023
At the end of the 19th century, projective geometry was at the basis of most geometric research in Italy, and of much other research work in Europe. Furthermore, through its close connection with descriptive geometry, it seemed particularly responsive to
Marta Menghini
doaj  

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