Results 71 to 80 of about 4,801,270 (329)

Conceptual Issues for Noncommutative Gravity on Algebras and Finite Sets

open access: yes, 1999
We discuss some of the issues to be addressed in arriving at a definitive noncommutative Riemannian geometry that generalises conventional geometry both to the quantum domain and to the discrete domain.
Majid, S.
core   +2 more sources

SmallTalk: a novel small‐sized fusion tag for peptide expression and purification

open access: yesFEBS Open Bio, EarlyView.
The SmallTalk fusion tag allows for the efficient expression and purification of soluble recombinant proteins or peptides in Escherichia coli. Testing with SmallTalk‐GFP confirmed that the proteins were soluble and folded correctly, while SmallTalk‐Bin1b maintained its antimicrobial activity against various bacterial isolates. This streamlined workflow
Atika Tariq   +3 more
wiley   +1 more source

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

open access: yesFEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu   +5 more
wiley   +1 more source

Estimating impacts of emission specific characteristics on vehicle operation for quantifying air pollutant emissions and energy use

open access: yesJournal of Traffic and Transportation Engineering (English ed. Online), 2017
This paper proposes and illustrates a methodology to predict the fraction of time motor vehicles spend in different operating conditions from readily observable variables called emission specific characteristics (ESC).
K.S. Nesamani   +3 more
doaj   +1 more source

Free factorization algebras and homology of configuration spaces in algebraic geometry

open access: yes, 2017
We provide a construction of free factorization algebras in algebraic geometry and link factorization homology of a scheme with coefficients in a free factorization algebra to the homology of its (unordered) configuration spaces.
Ho, Q. P.
core   +1 more source

Interleukin‐6 as a Key Biomarker in Facioscapulohumeral Dystrophy: Evidence From Longitudinal Analyses

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Facioscapulohumeral muscular dystrophy type 1 (FSHD1) is a progressive neuromuscular disorder with no approved treatments. Identifying reliable biomarkers is critical to monitor disease severity, activity, and progression. Interleukin‐6 (IL‐6) has been proposed as a candidate biomarker, but longitudinal validation is limited ...
Jonathan Pini   +13 more
wiley   +1 more source

Study of kerf geometry of multilayers materials in abrasive water jet cutting process

open access: yesMATEC Web of Conferences, 2017
The use of abrasive jet cutting in case of multilayers materials, shows particularities and difficulties, due to different hardness and thickness of layers.
Barabas Bogdan, Deaconescu Andrea
doaj   +1 more source

Generalized $1$-harmonic Equation and The Inverse Mean Curvature Flow

open access: yes, 2010
We introduce and study generalized $1$-harmonic equations (1.1). Using some ideas and techniques in studying $1$-harmonic functions from [W1] (2007), and in studying nonhomogeneous $1$-harmonic functions on a cocompact set from [W2, (9.1)] (2008), we ...
Ai-Nung Wang   +20 more
core   +1 more source

Higher Amyloid and Tau Burden Is Associated With Faster Decline on a Digital Cognitive Test

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective A 2‐min digital clock‐drawing test (DCTclock) captures more granular features of the clock‐drawing process than the pencil‐and‐paper clock‐drawing test, revealing more subtle deficits at the preclinical stage of Alzheimer's disease (AD). A previous cross‐sectional study demonstrated that worse DCTclock performance was associated with
Jessie Fanglu Fu   +16 more
wiley   +1 more source

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