Results 121 to 130 of about 64,504 (272)
IntroductionSocial prescribing for children and young people (CYP) is expanding across England, yet there is limited understanding of how local services interpret and configure its core components—individual need, referrer, linking function and community
Vashti Berry +6 more
doaj +1 more source
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
Community link worker programme - mental health and wellbeing deep dive
This project reviewed the mental health and wellbeing workloads of Community Link Workers’ (CLW) in Glasgow. A Community Link Worker (CLW) is part of the GP practice team intended to support patients with a wide range of non-medical issues that may be ...
Conduit-Turner, Karen, Mekina, Maša
core
Workers’ Attitudes Towards Digital Transformation and Perceived Well-Being At Work: A Case Study
This study examines workers’ attitudes toward digital transformation and job well-being in the semiconductor industry, focusing on a major German manufacturer, to identify ergonomic and managerial potentials for improvement.
Lindner Fabian +3 more
doaj +1 more source
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Phosphoinositides and inositol phosphates as molecular glues
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry +9 more
wiley +1 more source
Social prescribing for informal carers: a pre-post study
Background Informal carers often experience compromised mental and physical wellbeing due to their caring responsibilities. While social prescribing shows promise in supporting various populations, evidence for its effectiveness in supporting carers is ...
Christina Aggar +4 more
doaj +1 more source
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara +3 more
wiley +1 more source
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source

