Results 81 to 90 of about 1,334,769 (343)

Linkage Memory in Underivatized Protonated Carbohydrates [PDF]

, 2020
Carbohydrates are among the most complex class of biomolecules and even subtle variations in their structures are attributed to diverse biological function.
Miklos, Guttman, Abhigya, Mookherjee, Sanjit S., Uppal, Taylor A., Murphree   +3 more
core   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Mutant Huntingtin Affects Diabetes and Alzheimer’s Markers in Human and Cell Models of Huntington’s Disease

Cells, 2019
A higher incidence of diabetes was observed among family members of individuals affected by Huntington’s Disease with no follow-up studies investigating the genetic nature of the observation.
Gepoliano Chaves, John Stanley, Nader Pourmand   +2 more
doaj   +1 more source

Record-Linkage from a Technical Point of View [PDF]

TRecord linkage is used for preparing sampling frames, deduplication of lists and combining information on the same object from two different databases.
Rainer Schnell
core  

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Regression analysis under probabilistic multi-linkage

, 2012
"Linkage errors can occur when probability-based methods are used to link records from two distinct data sets corresponding to the same target population.
Gunky Kim (20124087), Raymond Chambers (19586527)   +1 more
core   +1 more source

A novel protocol for a "Citizen Panel" for diverse Public and Participant Involvement in the review and development of the process to access data in the UK Longitudinal Linkage Collaboration Trusted Research Environment

International Journal of Population Data Science
Background Researchers can apply to UK Longitudinal Linkage Collaboration (UK LLC) to access Longitudinal Population Study (LPS) data linked to health, non-health administrative and geo-environmental data.
Lidis Garbovan, Betty O. Idemudia, Robin Flaig, Kirsteen Campbell, Katharine Evans, Andy Boyd, Sarah Cunningham-Burley, Emma L. Turner   +7 more
doaj   +1 more source

LinkageMapView—rendering high-resolution linkage and QTL maps

Bioinform., 2017
Motivation Linkage and quantitative trait loci (QTL) maps are critical tools for the study of the genetic basis of complex traits. With the advances in sequencing technology over the past decade, linkage map densities have been increasing dramatically ...
Lisa A. Ouellette, Robert W. Reid, Steven G. Blanchard, Cory R. Brouwer   +3 more
semanticscholar   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source