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Linkage Analysis

2020
Abstract Linkage analysis is a framework for determining the impact that employee attitudes, as measured by organizational surveys, have on business outcomes. Linking employee attitudes to outcomes such as employee turnover and performance provides a compelling business case for executives to invest both emotionally and financially in ...
Shawn M. Del Duco   +3 more
openaire   +1 more source

Use of LINKAGE Programs for Linkage Analysis

Current Protocols in Human Genetics, 2001
AbstractThis unit provides an introduction to human genetic linkage analysis for cases in which the genetic model is known (parametric or lod score linkage analysis). The LINKAGE computer package is used for computer analysis because it remains a training standard.
openaire   +2 more sources

LINKAGE Programs: Linkage Analysis for Monogenic Cardiovascular Diseases

2006
Identification of the genes for a human disease provides significant insights into the molecular mechanism underlying the pathogenesis of the disease. A human disease gene can be identified by its chromosomal location (positional cloning). Linkage analysis is a key step in positional cloning.
Lin, Li, Qing K, Wang, Shaoqi, Rao
openaire   +2 more sources

Linkage analysis with cohort effects: An application to X‐linkage

Genetic Epidemiology, 1989
AbstractThe LIPED program has been modified to incorporate cohort effects in a linkage analysis. Very significant positive lod scores are obtained between bipolar affective disorder and both the deutan and protan markers on the X‐chromosome. Lod score methods are shown to be sensitive to the specification of the age onset distributions and the ...
openaire   +2 more sources

Software for genetic linkage analysis

Molecular Biotechnology, 1996
Recent developments in human genetic linkage analysis have included the appearance of new software and collections of data and program resources, accessible by means of the Internet. Many of these new programs and collections are described, including their availability, literature background, and specific technical information.
openaire   +3 more sources

Linkage Analysis of Genetic Disorders

2003
Basic principles and methods of genetic analysis were covered in this chapter. The approaches of linkage analysis for Mendelian or complex disorders can be summarized in the following flowchart (Fig. 2). It is important that the clinical, analytical, and molecular investigators be involved in all steps in the process.
E W, Taylor   +3 more
openaire   +2 more sources

Parametric Linkage Analysis

2003
Lyle J, Palmer   +3 more
openaire   +2 more sources

The Linkage of Sulfonimidoyl Fluorides and Unactivated Alkenes via Hydrosulfonimidoylation

Angewandte Chemie - International Edition, 2022
Wei-Ping Deng, Daming Zeng
exaly  

Linkage Analysis

2008
Robert Hazelwood, Janet Warren
  +4 more sources

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