Results 91 to 100 of about 199,519 (335)

Molecular breeding of sugarcane using linkage disequilibrium maps and quantitative trait alleles : [Abstract W247] [PDF]

open access: yes, 2009
Sugarcane breeding generally involves forms of recurrent selection using overlapping generations of parent genotypes, with the number of parents used in the order of 100 to 400, depending on the size of the breeding program.
Butterfield, Mike   +3 more
core  

Impact of single nucleotide polymorphisms in leptin, leptin receptor, growth hormone receptor, and diacylglycerol acyltransferase (DGAT1) gene loci on milk production, feed, and body energy traits of UK dairy cows [PDF]

open access: yes, 2008
The impact of 9 single nucleotide polymorphisms (SNP) in the leptin (LEP), leptin receptor (LEPR), growth hormone receptor (GHR), and diacylglycerol acyltransferase (DGAT1) gene loci on daily milk production, feed intake, and feed conversion, and weekly ...
Banos, G.   +4 more
core   +1 more source

Comparative Single‐Cell Transcriptomic Atlas Reveals the Genetic Regulation of Reproductive Traits

open access: yesAdvanced Science, EarlyView.
A cross‐species single‐cell transcriptomic atlas of reproductive and central nervous system tissues from sheep and humans reveals conserved cellular programs and regulatory networks that regulated fertility. Integration with GWAS for sheep lifetime average litter size identifies UNC5–SLIT–BMP signaling as a core pathway coordinating neuroendocrine ...
Bingru Zhao   +8 more
wiley   +1 more source

Quantitative genetics theory for non-inbred populations in linkage disequilibrium

open access: yesGenetics and Molecular Biology, 2004
Although linkage disequilibrium, epistasis and inbreeding are common phenomena in genetic systems that control quantitative traits, theory development and analysis are very complex, especially when they are considered together.
José Marcelo Soriano Viana
doaj   +1 more source

Linkage Disequilibrium-Based Inference of Genome Homology and Chromosomal Rearrangements Between Species

open access: yesG3: Genes, Genomes, Genetics, 2020
The aim of this study was to analyze the genomic homology between cattle (Bos taurus) and buffaloes (Bubalus bubalis) and to propose a rearrangement of the buffalo genome through linkage disequilibrium analyses of buffalo SNP markers referenced in the ...
Daniel Jordan de Abreu Santos   +9 more
doaj   +1 more source

Genome‐Wide Association Analyses Reveal the Genetic Basis of EMS Mutagenesis Efficiency in Rice

open access: yesAdvanced Science, EarlyView.
Based on large‐scale screening of 420 rice accessions, GWAS identified the Rc locus as a key regulator of EMS mutagenesis efficiency. Functional Rc alleles enhance both seed survival and genome‐wide mutation frequency by boosting antioxidant enzyme activities (CAT, SOD, POD) and reducing oxidative damage.
Peizhou Xu   +9 more
wiley   +1 more source

Effects of the Ordering of Natural Selection and Population Regulation Mechanisms on Wright-Fisher Models

open access: yesG3: Genes, Genomes, Genetics, 2017
We explore the effect of different mechanisms of natural selection on the evolution of populations for one- and two-locus systems. We compare the effect of viability and fecundity selection in the context of the Wright-Fisher model with selection under ...
Zhangyi He, Mark Beaumont, Feng Yu
doaj   +1 more source

Multi‐Tissue Genetic Regulation of RNA Editing in Pigs

open access: yesAdvanced Science, EarlyView.
This study presents the first multi‐tissue map of RNA editing and its genetic regulation in pigs. By integrating RNA editing profiles, edQTL mapping, GWAS, and cross‐species comparisons, this work establishes RNA editing as a distinct regulatory layer linking genetic variation to complex traits, highlighting its functional and evolutionary significance.
Xiangchun Pan   +21 more
wiley   +1 more source

Exploring linkage disequilibrium [PDF]

open access: yesMolecular Ecology Resources, 2015
Linkage disequilibrium (LD, association of allelic states across loci) is poorly understood by many evolutionary biologists, but as technology for multilocus sampling improves, we ignoreLDat our peril. If we sample variation at 10 loci in an organism with 20 chromosomes, we can reasonably treat them as 10 ‘independent witnesses’ of the evolutionary ...
openaire   +1 more source

Competition between recombination and epistasis can cause a transition from allele to genotype selection [PDF]

open access: yes, 2009
Biochemical and regulatory interactions central to biological networks are expected to cause extensive genetic interactions or epistasis affecting the heritability of complex traits and the distribution of genotypes in populations. However, the inference
Neher, Richard A., Shraiman, Boris I.
core   +3 more sources

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