Results 91 to 100 of about 537,873 (344)
Advanced Science, EarlyView.Genome‐wide analyses indicate that reduced ventral diencephalon and thalamus volumes, along with decreased functional connectivity within the triple network (DMN/CEN/SN), are uniquely associated with the risk of major depression (MD) onset, compared to other similar severe psychiatric disorders.
Ming‐Min Xu +7 more
wiley +1 more source
Predicting the range of linkage disequilibrium [PDF]
Proceedings of the National Academy of Sciences, 2000 A generally accepted strategy in the mapping of a disease gene is to initially apply linkage analysis for an approximate estimate of the location of the trait gene and to subsequently make use of linkage disequilibrium (association) for a more accurate localization.
openaire +3 more sources
Inferring linkage disequilibrium from non-random samples†
BMC Genomics, 2010 Background Linkage disequilibrium (LD) plays a fundamental role in population genetics and in the current surge of studies to screen for subtle genetic variants affecting complex traits.
Hu Xiaohua +5 more
doaj +1 more source
BMC Evolutionary Biology, 2020 Background Many species are threatened with extinction as their population sizes decrease with changing environments or face novel pathogenic threats.
Christelle Vangenot +6 more
doaj +1 more source
Identification of Genetic Loci Associated with Quality Traits in Almond via Association Mapping. [PDF]
PLoS ONE, 2015 To design an appropriate association study, we need to understand population structure and the structure of linkage disequilibrium within and among populations as well as in different regions of the genome in an organism.
Carolina Font i Forcada +5 more
doaj +1 more source
Genomic Insights into the Origin, High Fecundity and Environmental Adaptation of Hu Sheep
Advanced Science, EarlyView.The Hu sheep diverged from the Small‐tailed Han sheep ≈1330 years ago, and subsequently migrated from northern to warm and humid southern regions. The genes BMPR1B, UNC5C, and GRID2 play a synergistic role in the superior reproductive traits of Hu sheep.
Zexuan Liu +12 more
wiley +1 more source
BMC Genomics, 2009 Background It is well known that the pattern of linkage disequilibrium varies between human populations, with remarkable geographical stratification.
Navarro Arcadi +12 more
doaj +1 more source
G3: Genes, Genomes, Genetics, 2020 The aim of this study was to analyze the genomic homology between cattle (Bos taurus) and buffaloes (Bubalus bubalis) and to propose a rearrangement of the buffalo genome through linkage disequilibrium analyses of buffalo SNP markers referenced in the ...
Daniel Jordan de Abreu Santos +9 more
doaj +1 more source
Effects of Overlapping Generations on Linkage Disequilibrium Estimates of Effective Population Size
Genetics, 2014 Use of single-sample genetic methods to estimate effective population size has skyrocketed in recent years. Although the underlying models assume discrete generations, they are widely applied to age-structured species.
R. Waples, T. Antão, G. Luikart
semanticscholar +1 more source
American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, EarlyView.ABSTRACT Schizophrenia is a neurodevelopmental psychiatric disorder characterized by symptoms of psychosis, thought disorder, and flattened affect. Immune mechanisms are associated with schizophrenia, though the precise nature of this relationship (causal, correlated, consequential) and the mechanisms involved are not fully understood.
David Stacey +6 more
wiley +1 more source