Results 91 to 100 of about 177,696 (251)

A new genomic resource to enable standardized surveys of SNPs across the native range of brook trout (Salvelinus fontinalis)

Molecular Ecology Resources, EarlyView., 2023
Abstract Understanding how genetic diversity is distributed across spatiotemporal scales in species of conservation or management concern is critical for identifying large‐scale mechanisms affecting local conservation status and implementing large‐scale biodiversity monitoring programmes.
Nadya R. Mamoozadeh, Andrew R. Whiteley, Benjamin H. Letcher, David C. Kazyak, Charlene Tarsa, Mariah H. Meek   +5 more
wiley   +1 more source

Association mapping in tetraploid potato [PDF]

, 2009
The results of a four year project within the Centre for BioSystems Genomics (www.cbsg.nl), entitled “Association mapping and family genotyping in potato” are described in this thesis.
hoop, B.B., D'
core  

Gene-history correlation and population structure

, 2004
Correlation of gene histories in the human genome determines the patterns of genetic variation (haplotype structure) and is crucial to understanding genetic factors in common diseases.
Eriksson A Mehlig B, Griffiths R C, Griffiths R C, Hill W G, Hudson P R, Hudson R, Hudson R R, Hudson R R, Kaplan N, Kong A, Kuhner M K, McPeek M S, McVean G, McVean G, Nielsen R, Pluzhnikov A, Slatkin M, Tajima F, Tajima F   +18 more
core   +2 more sources

Dual‐Responsive Multi‐Functional Silica Nanoparticles With Repaired Mitochondrial Functions for Efficient Alleviation of Spinal Cord Injury

Exploration, EarlyView.
Targeting mitochondrial dysfunction presents a potential therapeutic approach for treating spinal cord injury. We have successfully designed and synthesized a functional Se@NADH nanodrug system. This system offers neuroprotective and neuroregenerative benefits by modulating mitochondrial function and neutralizing reactive oxygen species, thereby ...
Guibin Gao, Juanjuan Li, Yanming Ma, Min Xie, Jianxian Luo, Ke Wang, Cheng Peng, Hua Yang, Tianjun Chen, Guowei Zhang, Jiang Ouyang, Hongsheng Lin, Zhisheng Ji   +12 more
wiley   +1 more source

Scaling‐up RADseq methods for large datasets of non‐invasive samples: Lessons for library construction and data preprocessing

Molecular Ecology Resources, EarlyView., 2023
Abstract Genetic non‐invasive sampling (gNIS) is a critical tool for population genetics studies, supporting conservation efforts while imposing minimal impacts on wildlife. However, gNIS often presents variable levels of DNA degradation and non‐endogenous contamination, which can incur considerable processing costs. Furthermore, the use of restriction‐
Larissa S. Arantes, Jilda A. Caccavo, James K. Sullivan, Sarah Sparmann, Susan Mbedi, Oliver P. Höner, Camila J. Mazzoni   +6 more
wiley   +1 more source

Multi‐Cohort Analysis Reveals Genetic Predispositions to Clonal Hematopoiesis as Mutation‐Specific Risk Factors for Stroke

Advanced Genetics, Volume 6, Issue 1, March 2025.
This study comprehensively evaluated the differential effect of clonal hematopoiesis (CH) mutations on the risk of various stroke subtypes and functional recovery. It shows that TET2 is associated with small vessel stroke possibly via a pro‐inflammatory pathway. Abstract Recent observational studies have found an association between Clonal Hematopoesis
Shuyang Lin, Yang E. Li, Yan Wang
wiley   +1 more source

Evolutionary history and seascape genomics of Harbour porpoises (Phocoena phocoena) across environmental gradients in the North Atlantic and adjacent waters

Molecular Ecology Resources, EarlyView., 2023
Abstract The Harbour porpoise (Phocoena phocoena) is a highly mobile cetacean species primarily occurring in coastal and shelf waters across the Northern hemisphere. It inhabits heterogeneous seascapes broadly varying in salinity and temperature. Here, we produced 74 whole genomes at intermediate coverage to study Harbour porpoise's evolutionary ...
Enrique Celemín, Marijke Autenrieth, Anna Roos, Iwona Pawliczka, María Quintela, Ulf Lindstrøm, Harald Benke, Ursula Siebert, Christina Lockyer, Per Berggren, A. Amaha Özturk, Bayram Özturk, Véronique Lesage, Ralph Tiedemann   +13 more
wiley   +1 more source

Proteome‐Wide Mendelian Randomization Identifies Candidate Causal Proteins for Cardiovascular Diseases

Advanced Genetics, EarlyView.
Here, causal relations are examined between 2940 plasma proteins and 19 cardiovascular diseases (CVD) using a human genetics‐based method. 218 proteins are found whose blood levels influence CVD risks, with about half being new discoveries and largely confirmed in an independent cohort.
Chen Li, Nicolas De Jay, Shan‐Shan Zhang, Xin Fang, Supriya Sharma, Katrina A. Catalano, Venkatesh Sridharan, Zhaoqing Wang, Lei Zhao, Joseph D. Szustakowski, Ching‐Pin Chang, Joseph C. Maranville, Emily R. Holzinger, Erika M. Kvikstad   +13 more
wiley   +1 more source

Evaluating restriction enzyme selection for reduced representation sequencing in conservation genomics

Molecular Ecology Resources, EarlyView., 2023
Abstract Conservation genomic studies in non‐model organisms generally rely on reduced representation sequencing techniques based on restriction enzymes to identify population structure as well as candidate loci for local adaptation. While the expectation is that the reduced representation of the genome is randomly distributed, the proportion of the ...
Ainhoa López, Carlos Carreras, Marta Pascual, Cinta Pegueroles   +3 more
wiley   +1 more source

Individual‐based landscape genomics for conservation: An analysis pipeline

Molecular Ecology Resources, EarlyView., 2023
Abstract Landscape genomics can harness environmental and genetic data to inform conservation decisions by providing essential insights into how landscapes shape biodiversity. The massive increase in genetic data afforded by the genomic era provides exceptional resolution for answering critical conservation genetics questions.
E. Anne Chambers, Anusha P. Bishop, Ian J. Wang   +2 more
wiley   +1 more source