Results 121 to 130 of about 177,696 (251)

Associations Between Lipids and Lipid‐Lowering Drug Target Genes and Osteomyelitis: A Mendelian Randomization Analysis

Medicine Advances, EarlyView.
In this study, we identified several SNPs in PCSK9 as genetic tools to comprehensively assess the influential role of PCSK9 in CHD, CRP, and osteomyelitis. PCSK9 is associated with a lower risk of osteomyelitis, and PCSK9 is also associated with a reduction in CRP concentrations. Our study supports the notion that WC may be a potential mediator between
Zhiyi Zhou, Zhehan Yang, Junpan Chen, Minghao Wen, Jiayuan Lei, Wanzhe Liao, Yahan Li, Linghui Liu, Ziyuan Lu   +8 more
wiley   +1 more source

Genetic diversity, linkage disequilibrium, and population structure of tetraploid wheat landraces originating from Europe and Asia. [PDF]

BMC Genomics, 2023
Rabieyan E, Darvishzadeh R, Mohammadi R, Gul A, Rasheed A, Akhar FK, Abdi H, Alipour H.   +7 more
europepmc   +1 more source

Population genomic analyses reveal extensive genomic regions within selective sweeps associated with adaptation and demographic history of a wheat fungal pathogen

New Plant Protection, EarlyView.
Applying population genomics, this study revealed that Pst exhibits slower linkage disequilibrium decay compared to rust fungi with known sexual reproduction, identified extensive hard and soft sweeps linked to Pst adaptation, and demonstrated that crop domestication and breeding programs have significantly influenced pathogen population sizes ...
Yun Xing, Chongjing Xia, Liang Huang, Na Zhao, Hongfu Li, Xingzong Zhang, Age Qiu, Wanqiang Tang, Meinan Wang, Xianming Chen, Bo Liu, Hao Zhang, Li Gao, Wanquan Chen, Taiguo Liu   +14 more
wiley   +1 more source

LDmat: efficiently queryable compression of linkage disequilibrium matrices. [PDF]

Bioinformatics, 2023
Weiner RJ, Lakhani C, Knowles DA, Gürsoy G.   +3 more
europepmc   +1 more source

Occurrence and integrated control of major rice diseases in China

New Plant Protection, EarlyView.
Rice is constantly under threat from a variety of pathogens. This review highlights the major diseases affecting rice in China, including three fungal diseases, two bacterial diseases, two viral diseases, and one nematode. The review also proposes future directions for an integrated approach to control these significant rice diseases.
Ruyi Wang, Zhiyuan Ji, Yanjun Kou, Xiuling Yang, Wenkun Huang, Zongtao Sun, Shimin Zuo, Zhiqiang Li, Yehui Xiong, Yiwen Deng, Xueping Zhou, Guo‐Liang Wang, Jie Liu, Yuese Ning   +13 more
wiley   +1 more source

Prey and prejudice: predation by the European bee‐eater Merops apiaster has species‐specific effects on the ecology and genetics of bumblebees

Oikos, EarlyView.
Predation is a major ecological force, but its effect on bees has rarely been studied. Here, we investigated whether the presence of the European bee‐eater Merops apiaster, a migratory bird species and major bee predator, decreases the abundance and body size of three common bumblebee species (Bombus lapidarius, B. terrestris and B.
Belinda Kahnt, Andreas Etel, Felix Jarosch, Oliver Schweiger, Atilla Çelikgil, Panagiotis Theodorou   +5 more
wiley   +1 more source

The Linkage-Disequilibrium and Recombinational Landscape in Daphnia pulex. [PDF]

Genome Biol Evol, 2022
Lynch M, Ye Z, Urban L, Maruki T, Wei W.
europepmc   +1 more source

Integrating target capture with whole genome sequencing of recent and natural history collections to explain the phylogeography of wild‐growing and cultivated cannabis

PLANTS, PEOPLE, PLANET, EarlyView.
Cannabis has been used by humans for millennia, resulting in diverse landraces and uses. Its complex legal status and economic importance make sampling wild‐growing populations difficult, limiting past studies to modern cultivars with low genetic diversity. Our research provides crucial insights into the genetic diversity of wild‐growing and cultivated
Manica Balant, Daniel Vitales, Zhiqiang Wang, Zoltán Barina, Lin Fu, Tiangang Gao, Teresa Garnatje, Airy Gras, Muhammad Qasim Hayat, Marine Oganesian, Jaume Pellicer, Seyed A. Salami, Alexey P. Seregin, Nina Stepanyan‐Gandilyan, Nusrat Sultana, Shagdar Tsooj, Magsar Urgamal, Joan Vallès, Robin van Velzen, Lisa Pokorny   +19 more
wiley   +1 more source

Estimating linkage disequilibrium and selection from allele frequency trajectories. [PDF]

Genetics, 2023
Li Y, Barton JP.
europepmc   +1 more source

Maslinic Acid Ameliorates DSS‐Induced Experimental Colitis by Suppressing Th Cell‐Mediated Inflammation via AICD Induction

Phytotherapy Research, EarlyView.
This study suggests that maslinic acid treatment protected intestinal mucosa and ameliorated gut inflammation, accompanied with significantly reduced inflammatory cytokines and Th cell infiltration and subset differentiation. In vitro, maslinic acid suppressed Th cell proliferation and differentiation, regulated cell cycle distribution, and decreased ...
Dan Li, Zhan‐dong Ye, Mu‐xia Li, Ying‐yi Luo, Can‐kun Zhou, Qing‐hua Mei, Cheng‐lai Xia, Song Huang, Ji‐yan Su   +8 more
wiley   +1 more source