Results 161 to 170 of about 199,519 (335)

Linkage Disequilibrium [PDF]

, 2020
openaire   +1 more source

Young adult self‐harm: The role of victimisation and polygenic risk in a population‐based longitudinal study

JCPP Advances, EarlyView.
Abstract Background Victimisation has been associated with self‐harm (with or without suicidal intent), but little is known about this association during young adulthood—a distinct developmental period. Further, not all individuals who experience victimisation will later engage in self‐harm, suggesting the influence of other factors.
Filip Marzecki, Isabelle Ouellet‐Morin, Helena M. S. Zavos, Sylvana Côté, Richard E. Tremblay, Jean‐Philippe Gouin, Massimiliano Orri, Michel Boivin, Marie‐Claude Geoffroy   +8 more
wiley   +1 more source

Efficient estimation for large-scale linkage disequilibrium patterns of the human genome. [PDF]

Elife, 2023
Huang X, Zhu TN, Liu YC, Qi GA, Zhang JN, Chen GB.   +5 more
europepmc   +1 more source

Multiple Sclerosis in Sardinia Is Associated and in Linkage Disequilibrium with HLA-DR3 and -DR4 Alleles

, 1997
Maria Giovanna Marrosu, Maria Rita Murru, Gianna Costa, Francesco Cucca, Stefano Sotgiu, Giulio Rosati, Francesco Muntoni   +6 more
openalex   +1 more source

Genomewide Linkage Disequilibrium Mapping of Severe Bipolar Disorder in a Population Isolate [PDF]

, 2002
Roel A. Ophoff, Michael Escamilla, Susan K. Service, Mitzi Spesny, Dar Meshi, Wingman Poon, Julio Molina, Eduardo Fournier, Álvaro Gallegos, Carol A. Mathews, Thomas C. Neylan, Steven L. Batki, Erin Roche, Margarita Ramirez, Sandra Silva, Melissa C. De Mille, Penny Dong, Pedro León, Victor I. Reus, Lodewijk A. Sandkuijl, Nelson B. Freimer   +20 more
openalex   +1 more source

gap: Genetic Analysis Package [PDF]

A preliminary attempt at collecting tools and utilities for genetic data as an R package called gap is described. Genomewide association is then described as a specific example, linking the work of Risch and Merikangas (1996), Long and Langley (1997) for
Jing Hua Zhao
core   +1 more source

Investigating the impact of early adversity on perceived support from parents and friends in preadolescence: Do genetic predispositions and timing of exposure matter?

JCPP Advances, EarlyView.
This study found that youth with a higher genetic risk for internalizing and externalizing problems were more likely to face adversity within their home, highlighting the need for risk mitigation. These associations varied by adversity type and timing. Additionally, low family income, parental divorce, and externalizing behaviours were linked to lower ...
Christina Y. Cantave, Marthe de Roo, Charlotte Vrijen, Tina Kretschmer   +3 more
wiley   +1 more source

Integrative Genomics Reveals Causal Pleiotropy and Therapeutic Opportunities at the Interface of Acute Pancreatitis and Infection

Journal of Hepato-Biliary-Pancreatic Sciences, EarlyView.
ABSTRACT Background Understanding the genetic links between acute pancreatitis (AP) and its infectious comorbidities is crucial for prognosis and therapy, yet remains underexplored. Methods We conducted a comprehensive post‐GWAS analysis using large‐scale summary statistics for AP and 16 infectious diseases. To pinpoint pleiotropic genes, we integrated
Bo Zou, Hao Jiang, Jingsheng Ruan, Daifeng Yang, Xing Chen, Shanshan Cai, Xinglin Yi   +6 more
wiley   +1 more source

Linkage Disequilibrium Decay and Haplotype Block Structure in the Pig [PDF]

, 2008
Andreia J. Amaral, Hendrik‐Jan Megens, R.P.M.A. Crooijmans, H.C.M. Heuven, Martien A. M. Groenen   +4 more
openalex   +1 more source

Genome‐wide association study of periodontitis severity and progression

Journal of Periodontology, EarlyView.
Abstract Background To add to the knowledge base of periodontal genomics, we carried out a genome‐wide association study (GWAS) of periodontitis severity and progression among 416 mixed‐ethnicity adult participants of a periodontitis clinical study. Methods Participants were 168 adults (mean age = 50 years, 46% males) with severe periodontitis and 248 ...
Flavia Teles, Ganesh Chandrasekaran, Lynn Martin, Poojan Shrestha, Kevin Moss, Michele Patel, Michael J. Kallan, Camila Furquim, Andrew J. Cucchiara, James D. Beck, Kari E. North, Joseph Glessner, Kimon Divaris   +12 more
wiley   +1 more source