Results 201 to 210 of about 127,775 (292)

Heat Tolerance Limits in Indoor Environments: Prolonged Fixed‐Condition Exposure Versus Humidity‐Ramp Protocols

Safety Science and Technology, EarlyView.
Fast ramp humidity protocols systematically underestimate human heat tolerance by failing to match physiological equilibration timescales. Prolonged fixed‐condition exposures reveal substantially higher sustainable wet‐bulb limits, supporting their use as the gold standard and motivating slower, equilibration‐based ramp designs for accurate heat risk ...
Fèlix Faming Wang, Yi Xu, Wentao Wu
wiley   +1 more source

Integrative Analysis of Plasma Proteome and Genome Reveals Novel Drug Targets for Chronic Rhinosinusitis and Nasal Polyps

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Background Chronic rhinosinusitis (CRS) and nasal polyps (NP) are chronic inflammatory conditions with unsatisfactory treatment outcomes due to frequent recurrence of refractory disease. Identifying new therapeutic targets is essential. Methods We conducted a proteome‐wide Mendelian randomization (MR) analysis by integrating genome‐wide ...
En Zhou, Shi Luo, Yu Xiao, Bin Liu, Xu‐Ping Xiao   +4 more
wiley   +1 more source

Admixed and single-continental genome segments of the same ancestry have distinct linkage disequilibrium patterns. [PDF]

Genome Biol
Lee H, Lee MH, Hou K, Pasaniuc B, Han B.
europepmc   +1 more source

Sex Hormones and the Risk of Nasal Polyps: A Two‐Sample Mendelian Randomization Study

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Objective The pathophysiological roles of sex hormones in airway inflammation have drawn much attention recently. We aimed to explore the causal effect of sex hormones on chronic rhinosinusitis (CRS) and nasal polyps (NP) via a Mendelian randomization (MR) study.
Ying Zhu, Jia‐Yao Zhou, Shi‐Yao Zhang, Ru Tang, Chun‐Yu Luo, Yue‐Long Gu, Zhi‐Peng Li, Wei‐Tian Zhang   +7 more
wiley   +1 more source

Noninvasive detection of twin zygosity using genome-wide linkage disequilibrium information. [PDF]

Clin Transl Med
Kong L, Yang Y, Yuan C, Wei X, Zhou X, Zhou J, Xing Y, Zou G, Sun Q, Cai L, Liang Q, Zhang Y, Wang H, Liu Z, Wu D, Sun L.   +15 more
europepmc   +1 more source

Obstructive Sleep Apnea and BMI, Body Fat Percentage in the East Asian Population: A Bidirectional and Multivariate Mendelian Randomization Study

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Objective To explore the causal relationship between obstructive sleep apnea and body fat percentage and body mass index (BMI) in the East Asian population by using bidirectional Mendelian randomization and multivariate Mendelian randomization.
Rui Fan, Wen‐Jun Lu, Hua Zhang, Hai‐Ling Jiang, Tao Li, Yan Yan   +5 more
wiley   +1 more source

Genetic linkage disequilibrium of deleterious mutations in threatened mammals. [PDF]

EMBO Rep
Hu C, Liu G, Zhang Z, Pan Q, Zhang X, Liu W, Li Z, Li M, Zhu P, Ji T, Garber PA, Zhou X.   +11 more
europepmc   +1 more source

The Relationship Between Blood Lipids, Coagulation Indexes, Blood Homocysteine and Sudden Deafness: A Retrospective Study and Mendelian Randomization Analysis

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Background Certain blood components, including blood lipids, coagulation parameters, and homocysteine, have been suggested to correlate with the incidence and prognosis of sudden sensorineural hearing loss (SSNHL). However, the nature of these associations remains controversial.
Feng‐Xin Yang, Yu‐Wan Song, Yan Wang, Kun Zhao, Hu‐Hui‐Fen He, Jing‐Jing Qiu, Da‐Wei Liu, Bo Li, Yan Sun   +8 more
wiley   +1 more source

Mapping genes for quantitative traits using linkage disequilibrium

Genetics Selection Evolution, 1991
Goddard ME
doaj   +1 more source

Strong Linkage Disequilibrium and Proxy Effect of <i>PPP1R16A</i> rs109146371 for <i>DGAT1</i> K232A in Japanese Holstein Cattle. [PDF]

Genes (Basel)
Akiyama Y, Ando T, Nozaki N, Arif M, Ide Y, Wang S, Miura N.   +6 more
europepmc   +1 more source