Results 211 to 220 of about 186,640 (297)

Moderation of treatment outcomes by polygenic risk for alcohol‐related traits in placebo‐controlled trials of topiramate

Alcohol, Clinical and Experimental Research, Volume 49, Issue 6, Page 1297-1305, June 2025.
In a secondary analysis of data from two randomized controlled trials of topiramate in 285 individuals with alcohol use disorder (AUD), measures of genetic risk for problematic alcohol use (PAU) and time to relapse to any drinking (TR) and heavy drinking (THR) significantly moderated topiramate's effect on alcohol‐related problems.
Henry R. Kranzler, Zeal Jinwala, Christal N. Davis, Heng Xu, Joanna M. Biernacka, Hang Zhou, Rachel L. Kember, Joel Gelernter, Richard Feinn   +8 more
wiley   +1 more source

A method for determining potential parental contamination: linkage disequilibrium-based log-likelihood ratio analysis for IVF-PGT. [PDF]

Reprod Biol Endocrinol
Bo L, Dong F, Wu Z, Zhou A, Zhang Y, Kong L, Zhan L, Lu N, Qi L, Sun T, Liang B, Mao C.   +11 more
europepmc   +1 more source

CoPheScan: phenome-wide association studies accounting for linkage disequilibrium

, 2023
Manipur I, Reales G, Sul JH, Shin MK, Longerich S, Cortes A, Wallace C.   +6 more
europepmc   +1 more source

A Comparison of Methods for Gene-Based Testing That Account for Linkage Disequilibrium. [PDF]

Front Genet, 2022
Cinar O, Viechtbauer W.
europepmc   +1 more source

Loci for primary ciliary dyskinesia map to chromosome 16p12.1-12.2 and 15q13.1-15.1 in Faroe Islands and Israeli Druze genetic isolates [PDF]

, 2004
Amirav, I, Bisgaard, H, Chodhari, R, Chung, EMK, Faeroe, O, Gardiner, RM, Jeganathan, D, Luder, AS, Meeks, M, Mitchison, HM, Nielsen, K, Smyth, D   +11 more
core   +2 more sources

LIAN 3.0: detecting linkage disequilibrium in multilocus data [PDF]

, 2000
Bernhard Haubold, Richard R. Hudson
openalex   +1 more source

Multi‐ancestry genome‐wide association study of topiramate's effects on heavy alcohol use

Alcohol, Clinical and Experimental Research, Volume 49, Issue 6, Page 1197-1205, June 2025.
Topiramate reduces alcohol consumption, but genetic predictors of treatment response have not been identified. We conducted a GWAS in 8386 individuals from the Million Veteran Program, evaluating genetic variants associated with the change in alcohol consumption before and after initiating topiramate.
Christal N. Davis, Zeal Jinwala, Amy C. Justice, Christopher T. Rentsch, Henry R. Kranzler   +4 more
wiley   +1 more source

CoPheScan: phenome-wide association studies accounting for linkage disequilibrium. [PDF]

Nat Commun
Manipur I, Reales G, Sul JH, Shin MK, Longerich S, Cortes A, Wallace C.   +6 more
europepmc   +1 more source

The evolutionary patterns of barley pericentromeric chromosome regions, as shaped by linkage disequilibrium and domestication. [PDF]

Plant J, 2022
Chen YY, Schreiber M, Bayer MM, Dawson IK, Hedley PE, Lei L, Akhunova A, Liu C, Smith KP, Fay JC, Muehlbauer GJ, Steffenson BJ, Morrell PL, Waugh R, Russell JR.   +14 more
europepmc   +1 more source

Evaluating linkage and linkage disequilibrium: use of excess sharing and transmission disequilibrium methods in affected sib pairs [PDF]

, 2000
Jacqueline Wicks, Susan R. Wilson
openalex   +1 more source