Results 91 to 100 of about 2,559,621 (312)

Haploidentical Hematopoietic Cell Transplantation for Infants With X‐Linked Severe Combined Immunodeficiency Using Post‐Transplant Cyclophosphamide

Pediatric Blood &Cancer, EarlyView.
Shuhei Takahashi, Akito Kawachi, Dan Tomomasa, Eri Watanabe, Yuji Fujita, Yuya Sato, Masahiro Sekiguchi, Kentaro Watanabe, Moe Hidaka, Akihiro Hoshino, Takahiro Kamiya, Masatoshi Takagi, Hirokazu Kanegane, Motohiro Kato   +13 more
wiley   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Lycaeides melissa linkage map

, 2018
Text file describing the L. melissa linkage map. There are three columns giving the linkage group (lg), scaffold number (scaf, these match the reference genome scaffold names), and position (pos) in centi Morgans along the relevant linkage ...
Gompert, Zach, Lucas, Lauren, Lauren Lucas (3288597), Chris Nice (5017265), Zach Gompert (3191738), Nice, Chris   +5 more
core   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Kermit: linkage map guided long read assembly

Algorithms for Molecular Biology, 2019
Background  With long reads getting even longer and cheaper, large scale sequencing projects can be accomplished without short reads at an affordable cost.
Riku Walve, Pasi Rastas, Leena Salmela
doaj   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Alignment of the linkage map, physical map, and sequence of the chicken genome

, 2004
Four BAC libraries constructed at Texas A&M University and at the Children's Hospital of Oakland Research Institute providing altogether ~28X coverage of the chicken genome have been screened with most of the suitable genes and markers that are found on ...
Rondelli, Catherine M, Dodgson, Jerry B, Romanov, Michael N   +2 more
core  

A second-generation genetic linkage map for bighead carp (Aristichthys nobilis) based on microsatellite markers

, 2014
Bighead carp (Aristichthys nobilis) is an important aquaculture fish worldwide. Genetic linkage maps for the species were previously reported, but map resolution remained to be improved.
Yu, X., Liu, L., Tong, J., Fu, B., Zhu, C., Liu, H., Wang, X., Sun, Y., Guo, W., Feng, X.   +9 more
core   +1 more source

Duck (Anas platyrhynchos) linkage mapping by AFLP fingerprinting

Genetics Selection Evolution, 2009
Amplified fragment length polymorphism (AFLP) with multicolored fluorescent molecular markers was used to analyze duck (Anas platyrhynchos) genomic DNA and to construct the first AFLP genetic linkage map. These markers were developed and genotyped in 766
Yang Kuo-Tai, Rouvier Roger, Cheng Yu-Shin, Huang Chang-Wen, Wu Chean-Ping, Huang Hsiu-Lin, Huang Mu-Chiou   +6 more
doaj   +1 more source