Results 101 to 110 of about 2,559,621 (312)

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

A microsatellite linkage map of Drosophila mojavensis

BMC Genetics, 2004
Background Drosophila mojavensis has been a model system for genetic studies of ecological adaptation and speciation. However, despite its use for over half a century, no linkage map has been produced for this species or its close relatives.
Schully Sheri, Staten Regina, Noor Mohamed AF   +2 more
doaj   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

Linkage map data for Acropora millepora

, 2015
2bRAD-based linkage map ...
Sarah W. Davies (455980), Mikhail V. Matz (51701), Line K. Bay (411810), Matz, Mikhail V., E. Meyer (3282588), Galina A. Aglyamova (3282585), Bay, Line K., Aglyamova, Galina A., Davies, Sarah W., Meyer, E., Groves B. Dixon (3282582), Dixon, Groves B.   +11 more
core   +1 more source

Genomewide linkage scan of schizophrenia in a large multicenter pedigree sample using single nucleotide polymorphisms [PDF]

, 2009
A genomewide linkage scan was carried out in eight clinical samples of informative schizophrenia families. After all quality control checks, the analysis of 707 European-ancestry families included 1615 affected and 1602 unaffected genotyped individuals ...
D Walsh, Gejman, P. V., D F Levinson, Alexander, M., Ribble, R, Mallet, J., Wormley, B., Godard, S, O'Neill, A., Dikeos, D., Alexander, M, Owen, Michael John, F B Lerer, Holmans, PA, Wormley, B, O'Donovan, MC, Liang, KY, R R Crowe, Norton, N., Jay, M., Nertney, D., Silverman, J. M., Levinson, D. F., Mowry, Bryan, Sanders, A. R., Nestadt, G., P A Holmans, Walsh, D., Pulver, A. E., V K Lasseter, Laurent, C, Kendler, K. S., A O'Neill, A E Pulver, C Laurent, Holmans, Peter Alan, G Nestadt, M J Owen, M Alexander, Holmans, P. A., O'Donovan, Michael Conlon, D B Wildenauer, Albus, M., O'Neill, Anthony, Norton, N, P V Gejman, Gejman, PV, Wildenauer, DB, M Albus, Maier, W, Williams, N. M., Nestadt, G, Schwab, SG, G Papadimitriou, Nertney, D, Papadimitriou, G, Lasseter, V. K., D Nertney, Liang, K. Y., Lerer, F. B., Lasseter, VK, O'Donovan, M. C., Duan, J., K S Kendler, Mallet, J, O'Neill, A, N M Williams, J Duan, Mowry, B. J., Duan, J, B Riley, D Dikeos, Owen, M. J., M C O'Donovan, B J Mowry, J Mallet, Owen, MJ, Laurent, C., Norton, Nadine, Jay, M, Crowe, R. R., B Wormley, Maier, W., Albus, M, Walsh, D, R Ribble, Schwab, S. G., S G Schwab, S Godard, N Norton, W Maier, Papadimitriou, G., M Jay, Riley, B, Williams, Nigel Melville, Kendler, KS, Williams, NM, A R Sanders, Lerer, FB, Riley, B., K Y Liang, Pulver, AE, Sanders, AR, Godard, S., Ribble, R., Wildenauer, D. B., J M Silverman   +106 more
core   +2 more sources

Near-saturated and complete genetic linkage map of black spruce (Picea mariana)

BMC Genomics, 2010
Background Genetic maps provide an important genomic resource for understanding genome organization and evolution, comparative genomics, mapping genes and quantitative trait loci, and associating genomic segments with phenotypic traits.
Mann Ishminder K, Kang Bum-Yong, Major John E, Rajora Om P   +3 more
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Green Map Flushing Meadow Queens NY

, 2005
A map of Flushing Meadows Corona Park in Queens, NY, site of two world fairs (1939 and 1964) currently home to a number of recreation facilities and green space.
Green Map System (Firm)
core  

A linkage map of spring turnip rape based on RFLP and RAPD markers

Agricultural and Food Science, 2008
A linkage map of spring turnip rape (Brassica rapa ssp. oleifera) was constructed from an F2 population of a cross Jo4002 x Sv3402. The map contained 22 RFLP loci, 144 RAPDs, one microsatellite, and one morphological marker (seed colour). All ten B. rapa
P.K. TANHUANPÄÄ, J.P. VILKKI, H.J. VILKKI   +2 more
doaj  

High-density SNP genetic linkage map construction and quantitative trait locus mapping for resistance to cucumber mosaic virus in tobacco (Nicotiana tabacum L.)

Crop Journal, 2019
Genetic linkage maps are essential for studies of genetics, genomic structure, and genomic evolution, and for mapping quantitative trait loci (QTL).
Lirui Cheng, Xiaocui Chen, Caihong Jiang, Bing Ma, Min Ren, Yazeng Cheng, Dan Liu, Ruimei Geng, Aiguo Yang   +8 more
doaj   +1 more source