Results 151 to 160 of about 6,712,199 (326)

Addressing persistent challenges in digital image analysis of cancer tissue: resources developed from a hackathon

open access: yesMolecular Oncology, EarlyView.
Large multidimensional digital images of cancer tissue are becoming prolific, but many challenges exist to automatically extract relevant information from them using computational tools. We describe publicly available resources that have been developed jointly by expert and non‐expert computational biologists working together during a virtual hackathon
Sandhya Prabhakaran   +16 more
wiley   +1 more source

Impact of molecular diagnostics and targeted cancer therapy on patient outcomes (MODIFY): a retrospective study of the implementation of precision oncology

open access: yesMolecular Oncology, EarlyView.
The authors conducted a retrospective study of 94 patients with advanced cancer who underwent next‐generation sequencing (NGS) gene panel analysis and received targeted treatments when applicable. Results further support evidence indicating that molecular profiling provides clinical benefit.
Michaël Dang   +3 more
wiley   +1 more source

Semantic technologies and linked data for the Italian PA: the case of data.cnr.it

open access: yesJLIS.it, 2013
Governmental data are being published in many countries, providing an unprecedented opportunity to create innovative services and to increase societal awareness about administration dynamics.
Aldo Gangemi
doaj   +2 more sources

Detection rate for ESR1 mutations is higher in circulating‐tumor‐cell‐derived genomic DNA than in paired plasma cell‐free DNA samples as revealed by ddPCR

open access: yesMolecular Oncology, EarlyView.
Analysis of ESR1 mutations in plasma cell‐free DNA (cfDNA) is highly important for the selection of treatment in patients with breast cancer. Using multiplex‐ddPCR and identical blood draws, we investigated whether circulating tumor cells (CTCs) and cfDNA provide similar or complementary information for ESR1 mutations.
Stavroula Smilkou   +11 more
wiley   +1 more source

RKBExplorer.com:A Knowledge Driven Infrastructure for Linked Data Providers

open access: yes, 2008
RKB Explorer is a Semantic Web application that is able to present unified views of a significant number of heterogeneous data sources. We have developed an underlying information infrastructure which is mediated by ontologies and consists of many ...
Glaser, Hugh   +2 more
core  

Targeted metabolomics reveals novel diagnostic biomarkers for colorectal cancer

open access: yesMolecular Oncology, EarlyView.
This study employed targeted metabolomic profiling to identify 302 distinct metabolites present in platelet‐rich plasma (PRP), revealing aberrant metabolic profiles amongst individuals diagnosed with colorectal cancer (CRC). Compared to carcinoembryonic antigen (CEA) and cancer antigen 19‐9 (CA199), our metabolite panel showed improved sensitivity ...
Zuojian Hu   +7 more
wiley   +1 more source

Semantic Web: Metadata, Linked Data, Open Data

open access: yesScience & Philosophy, 2015
What's the Semantic Web? What's the use? The inventor of the Web Tim Berners-Lee describes it as a research methodology able to take advantage of the network to its maximum capacity.
Vanessa Russo
doaj  

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