Results 151 to 160 of about 30,884,827 (363)
YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma
Molecular Oncology, EarlyView.The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy +9 more
wiley +1 more source
Empirical evaluation of Linked Data visualization tools
, 2020 Federico Desimoni, Laura Po
openalex +2 more sources
Emerging role of ARHGAP29 in melanoma cell phenotype switching
Molecular Oncology, EarlyView.This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster +3 more
wiley +1 more source
Molecular Oncology, EarlyView.In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern +7 more
wiley +1 more source
, 2014 This thesis investigated the concept of building link services as an extension of Linked Data to improve its navigability (thus improving the linking of the Web of Linked Data). The study first considered the Semantic Web URI and how an agent understands what a URI refers to when dereferencing it.
openaire +1 more source
Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids
Molecular Oncology, EarlyView.This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici +8 more
wiley +1 more source
Provenance in Linked Data Integration
, 2010 The open world of the (Semantic) Web is a global information space offering diverse materials of disparate qualities, and the opportunity to re-use, aggregate, and integrate these materials in novel ways. The advent of Linked Data brings the potential to
Gibbins, Nicholas +2 more
core
Molecular Oncology, EarlyView.This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert +13 more
wiley +1 more source
['VIAF and the linked data ecosystem', 'VIAF and the linked data ecosystem']
JLIS.it, 2022 Nathan Putnam
doaj +1 more source
Integrating public datasets using linked data: challenges and design principles
, 2010 The world is moving from a state where there is paucity of data to one of surfeit. These data, and datasets, are normally in different datastores and of different formats.
Correndo, Gianluca +7 more
core