Results 61 to 70 of about 28,046,348 (280)
Linked Data for Life Sciences [PDF]
Massive amounts of data are currently available and being produced at an unprecedented rate in all domains of life sciences worldwide. However, this data is disparately stored and is in different and unstructured formats making it very hard to integrate.
Amrapali Zaveri, Gökhan Ertaylan
openaire +4 more sources
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
Linked Heritage: achievements and next steps
Linked Heritage: achievements and next steps Linked Heritage is a Best Practice Network which includes ministries, responsible government agencies, content providers and aggregators, leading research centres, publishers and SMEs from 20 EU countries ...
Antonella Fresa
doaj
The PRELIDA project aims at building bridges across the Digital Preservation and Linked Data communities, raising awareness of already existing outcomes of Digital Preservation in the Linked Data communities, while at the same time posing new research questions for the preservation domain.
Meghini C, Molino A, Borri F, Galesi G
openaire +1 more source
The human gut microbiome across the life course
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source
Linked Data Authorization Platform
The expansion of the smart devices, the growing popularity of the social networks, and the wide spread of the corporate services impose huge amounts of heterogeneous data to be generated and stored in separate silos on a daily basis.
Riste Stojanov +3 more
doaj +1 more source

