Results 61 to 70 of about 3,423,786 (296)
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Linked Data Authorization Platform
IEEE Access, 2018 The expansion of the smart devices, the growing popularity of the social networks, and the wide spread of the corporate services impose huge amounts of heterogeneous data to be generated and stored in separate silos on a daily basis.
Riste Stojanov +3 more
doaj +1 more source
Replication for Linked Data [PDF]
, 2012 With the Semantic Web scaling up, and more triple-stores with update facilities being available, the need for higher levels of simultaneous triple-stores with identical information becomes more and more urgent. However, where such Data Replication approaches are common in the database community, there is no comprehensive approach for data replication ...
openaire +2 more sources
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
RDFS & OWL Reasoning for Linked Data
, 2014 Book chapterLinked Data promises that a large portion of Web Data will be usable as one big interlinked RDF database against which structured queries can be answered.
Umbrich, Jurgen +2 more
core +1 more source
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Linked Heritage: achievements and next steps
Archeomatica, 2013 Linked Heritage: achievements and next steps Linked Heritage is a Best Practice Network which includes ministries, responsible government agencies, content providers and aggregators, leading research centres, publishers and SMEs from 20 EU countries ...
Antonella Fresa
doaj
ERCIM News, 2013 The PRELIDA project aims at building bridges across the Digital Preservation and Linked Data communities, raising awareness of already existing outcomes of Digital Preservation in the Linked Data communities, while at the same time posing new research questions for the preservation domain.
Meghini C, Molino A, Borri F, Galesi G
openaire +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source