Results 51 to 60 of about 28,046,348 (280)
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
A Verified Algebra for Linked Data
, 2011 A foundation is investigated for the application of loosely structured data on the Web. This area is often referred to as Linked Data, due to the use of URIs in data to establish links.
Horne, Ross, Sassone, Vladimiro
core +2 more sources
A Research Agenda for Linked Closed Data
, 2011 While it is preferable that Linked Data is published without access or licence restrictions, there will always remain certain datasets which, perhaps due to financial considerations, cannot be published as Linked Open Data.
Gibbins, Nicholas +4 more
core +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
From MARC silos to Linked Data silos?
o-bib. Das offene Bibliotheksjournal, 2017 Libraries are opening up their bibliographic metadata as Linked Data. However, they have all used different data models for structuring their bibliographic data.
Osma Suominen, Nina Hyvönen
doaj +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Introduction to the Principles of Linked Open Data
The Programming Historian, 2017 This lesson offers a brief and concise introduction to Linked Open Data (LOD). No prior knowledge is assumed. Readers should gain a clear understanding of the concepts behind linked open data, how it is used, and how it is created.
Jonathan Blaney
doaj
Replication for Linked Data [PDF]
, 2012 With the Semantic Web scaling up, and more triple-stores with update facilities being available, the need for higher levels of simultaneous triple-stores with identical information becomes more and more urgent. However, where such Data Replication approaches are common in the database community, there is no comprehensive approach for data replication ...
openaire +2 more sources
Linking and Consuming Agricultural Big Data with Linked Data and KOS [PDF]
, 2015 This paper gives brief introduction about the big data, linked data and knowledge organization systems (KOS) and their relationships. As the authors mainly focus on the variety and value characteristics of big data, the linked data and KOS technologies are used to link and consume the large amounts of literature and scientific data in agricultural ...
Guojian Xian +4 more
openaire +2 more sources
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source