Results 31 to 40 of about 2,634,309 (286)

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Linked Logainm: enhancing library metadata using linked data of Irish place names [PDF]

, 2017
Linked Logainm is the newly created Linked Data version of Logainm.ie, an online database holding the authoritative hierarchical list of Irish and English language place names in Ireland.
Collins, Sandra, Decker, Stefan, Grant, Rebecca, Lopes, Nuno, Ó Carragáin, Eoghan, Ó Raghallaigh, Brian   +5 more
core   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source

RIP Linked List

, 2023
Linked lists have long served as a valuable teaching tool in programming. However, the question arises: Are they truly practical for everyday program use? In most cases, it appears that array-based data structures offer distinct advantages, particularly in terms of memory efficiency and,more importantly, execution speed.
Sonntag, Benoît, Colnet, Dominique
openaire   +2 more sources

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

A checklist of isopods (Crustacea: Isopoda) in Slovenia

Natura Sloveniae, 2023
Isopods are a diverse peracarid crustacean group with marine, freshwater and terrestrial representatives. Isopod species lists were typically prepared according to different habitats, which was true also for Slovenia. Here, we prepared the first unified
Miloš Vittori, Borut Mavrič, Anja Pekolj, Marijan Govedič, Maja Zagmajster   +4 more
doaj   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

Fast reliability evaluation method for composite power system based on the improved EDA and double cross linked list

IET Generation, Transmission & Distribution, 2017
To improve the computational efficiency of Monte Carlo simulation in composite power systems reliability evaluation, this study presents a method based on the improved estimation of distribution algorithm (EDA) and double cross linked list.
Wenxia Liu, Rui Cheng, Yahui Xu, Zongqi Liu   +3 more
doaj   +1 more source

Neighbourhood Abstraction in GROOVE - Tool Paper [PDF]

, 2010
In this paper we discuss the implementation of neighbourhood graph abstraction in the GROOVE tool set. Important classes of graph grammars may have unbounded state spaces and therefore cannot be verified with traditional model checking techniques.
Rensink, Arend, Zambon, Eduardo
core   +1 more source