Results 81 to 90 of about 2,634,309 (286)

Making using administrative data easier: How To Guides and the Phenotype Code List Repository for ECHILD

International Journal of Population Data Science
Objectives Even experienced researchers face difficulties in finding and using administrative data and producing analysis-ready datasets. Here we describe two resources developed to support users of the Education and Child Health Insights from Linked ...
Matthew Jay, Kate Lewis, Difei Shi, Rebecca Langella, Tony Stone, Sorcha Ní Chobhthaigh , Ania Zylbersztejn, Ruth Blackburn, Katie Harron   +8 more
doaj   +1 more source

Interactions between genes and environmental factors in asthma and atopy: new developments

Respiratory Research, 2001
Asthma and associated phenotypes are complex traits most probably caused by an interaction of multiple disease susceptibility genes and environmental factors.
Sengler Claudia, Lau Susanne, Wahn Ulrich, Nickel Renate   +3 more
doaj   +1 more source

Improved O(N) neighbor list method using domain decomposition and data sorting [PDF]

, 2004
The conventional Verlet table neighbor list algorithm is improved to reduce the number of unnecessary inter-atomic distance calculations in molecular simulations involving large amount of atoms.
Cheng, Min, Wang, Jian-Sheng, Yao, Zhenhua   +2 more
core  

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

Molecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli, Alessio Bevilacqua, Mathias Wenes, Denis Migliorini, Lars van der Veen, Sigrid S Skånland, Giusy Di Conza, Kjetil Taskén   +7 more
wiley   +1 more source

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

Do list size and remuneration affect GPs' decisions about how they provide consultations?

BMC Health Services Research, 2009
Background Doctors' professional behaviour is influenced by the way they are paid. When GPs are paid per item, i.e., on a fee-for-service basis (FFS), there is a clear relationship between workload and income: more work means more money.
Westert Gert P, de Bakker Dinny H, van den Berg Michael, van der Zee Jouke, Groenewegen Peter P   +4 more
doaj   +1 more source

Linked-List-Based Multibody Dynamics (MBDyn) Engine [PDF]

This new release of MBDyn is a software engine that calculates the dynamics states of kinematic, rigid, or flexible multibody systems. An MBDyn multibody system may consist of multiple groups of articulated chains, trees, or closed-loop topologies ...
Brain, Thomas, Ghosh, Tushar, Huynh, An, MacLean, John, Wuiocho, Leslie   +4 more
core   +1 more source

Farming across the years: temporal and spatial dimensions of learning organic farming [PDF]

, 2002
In organic farming, it is generally accepted that a long-term perspective spanning across the years is necessary for the sustainability of organic field management. This paper analyzes the crossing over of annual boundaries during an organic inspection
Koskimies, H., Seppänen, L.
core  

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Construction of a Numerical Model for SLM Based on Smoothed Particle Hydrodynamics

IEEE Access
Selective laser melting technology has significant advantages in the manufacturing of complex components, but the strong coupling of multiple physical fields in the dynamic behavior of the molten pool poses severe challenges to numerical simulation ...
Shanmin Zhang
doaj   +1 more source