Results 81 to 90 of about 619,805 (296)

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

open access: yesMolecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain   +10 more
wiley   +1 more source

Circular Linked List [PDF]

open access: yes, 2011
Struktur Data menjelaskan penggunaan linked list tanpa nilai nill pada medan ...
Dharmayanti, Dian
core  

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

open access: yesMolecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak   +10 more
wiley   +1 more source

The Networked Data Lab: What linked data can tell us about the elective care waiting list in the UK

open access: yesInternational Journal of Population Data Science
Existing research on NHS elective care backlogs in the UK predominantly focuses on aggregate waiting list figures. Until recently there has been little analysis that uses patient-level data to disaggregate the waiting list, or which uses linked data to ...
Tom Prendergast   +9 more
doaj   +1 more source

Validation of Linked Lists

open access: yesInternational Journal of Engineering and Advanced Technology, 2019
Numerous cyberinformaticians would concur that, had it not been for sensor arranges, the strong unification of dissipate/accumulate I/O and neural systems may never have happened. Truth be told, couple of electrical architects would differ with the advancement of deletion coding, which epitomizes the organized standards of machine learning [1].
N. Priya, C. Anuradha, B. Sundarraj
openaire   +1 more source

Single Linked List (word) [PDF]

open access: yes, 2014
Arsip Kuliah Online 2014 Linked List yang memiliki satu medan ...
Kuliah Online, Arsip
core   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

Making using administrative data easier: How To Guides and the Phenotype Code List Repository for ECHILD

open access: yesInternational Journal of Population Data Science
Objectives Even experienced researchers face difficulties in finding and using administrative data and producing analysis-ready datasets. Here we describe two resources developed to support users of the Education and Child Health Insights from Linked ...
Matthew Jay   +8 more
doaj   +1 more source

Single Linked List [PDF]

open access: yes, 2015
Arsip Kuliah Online 2015 Linked List yang memiliki satu buah pointer ...
Kuliah Online, Arsip
core  

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

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