Results 131 to 140 of about 3,705,766 (336)

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Online Index Extraction from Linked Open Data Sources [PDF]

open access: yes, 2014
The production of machine-readable data in the form of RDF datasets belonging to the Linked Open Data (LOD) Cloud is growing very fast. However, selecting relevant knowledge sources from the Cloud, assessing the quality and extracting synthetical ...
Benedetti, Fabio   +2 more
core  

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

Access to care: analysis of the geographical distribution of healthcare using Linked Open Data [PDF]

open access: green, 2022
Selene Báez Santamaría   +5 more
openalex   +1 more source

Practical Linked Data: Learning How to Create and Use Linked Data in the Real World [PDF]

open access: yes, 2014
Want to learn more about linked data? This session is intended for anyone interested in learning more about linked data, whether they are new to the subject or more advanced. We will begin by describing what linked data is.
Becknell, Elissah   +5 more
core   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

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