Results 161 to 170 of about 5,195,087 (380)
Using Linked Open Data and Semantic Integration to Search Across Repositories [PDF]
, 2015 The MBLWHOI Library is a partner in the GeoLink project, an NSF EarthCube Building Block, applying semantic technologies to enable knowledge discovery, sharing and integration.
GeoLink Project Group +2 more
core
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Linked Open Data for Libraries
, 2020 Presentation given at NVB 2011 Conference, The Netherlands.
openaire +1 more source
β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1
Molecular Oncology, EarlyView.Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero +8 more
wiley +1 more source
MusicKG: Representations of Sound and Music in the Middle Ages as Linked Open Data [PDF]
, 2019 Victoria Eyharabide +2 more
openalex +1 more source
Building ontologies from folksonomies and linked data: Data structures and Algorithms [PDF]
, 2012 We present the data structures and algorithms used in the approach for building domain ontologies from folksonomies and linked data. In this approach we extracts domain terms from folksonomies and enrich them with semantic information from the Linked ...
Corcho, Oscar +4 more
core +1 more source
Molecular Oncology, EarlyView.AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou +5 more
wiley +1 more source
The EBI RDF platform: linked open data for the life sciences [PDF]
, 2017 Motivation: Resource description framework (RDF) is an emerging technology for describing, publishing and linking life science data. As a major provider of bioinformatics data and services, the European Bioinformatics Institute (EBI) is committed to ...
Birney, Ewan +15 more
core
Molecular Oncology, EarlyView.PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham +21 more
wiley +1 more source